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Showing 1–2 of 2 results
Advanced filters: Author: Maria Kutera Clear advanced filters

  • High-throughput chemical ligand discovery is challenged by false positives. Here, authors introduce a scalable enantioselective affinity-selection mass spectrometry approach for proteome-wide ligand discovery with high sensitivity and selectivity

    • Xiaoyun Wang
    • Jianxian Sun
    • Levon Halabelian
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-10

  • Nie et al. describe a mechanism underlying the degradation of the histone methyltransferase NSD2 through the recruitment of FBXO22 E3 ligase, providing a chemical probe for NSD2 function study and targeted protein degradation.

    • David Y. Nie
    • John R. Tabor
    • Cheryl H. Arrowsmith
    Research
    Nature Chemical Biology
    Volume: 20, P: 1597-1607