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Author Correction: Cell Painting: a decade of discovery and innovation in cellular imaging

Srijit Seal
Maria-Anna Trapotsi
Anne E. Carpenter
Amendments and Corrections12 Dec 2024
Nature Methods

Volume: 22, P: 447
Cell Painting: a decade of discovery and innovation in cellular imaging

This Review synthesizes the literature from over 10 years of Cell Painting for image-based profiling and highlights how advances in this technology enable new biological discovery of cellular phenotypes and cell responses to perturbations.

Srijit Seal
Maria-Anna Trapotsi
Anne E. Carpenter
Reviews05 Dec 2024
Nature Methods

Volume: 22, P: 254-268
Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

To control transposable elements, fruit flies rely on distinct genomic regions called piRNA clusters. Here, new piRNA clusters were identified across diverse Drosophila species, displaying a conserved and specialised role in the control of endogenous retroviruses in ovarian somatic cells.

Jasper van Lopik
Azad Alizada
Benjamin Czech Nicholson
ResearchOpen Access13 Nov 2023
Nature Communications

Volume: 14, P: 1-17
A community effort to optimize sequence-based deep learning models of gene regulation

A benchmarking competition improves tools that predict how regulatory regions control gene expression.

Abdul Muntakim Rafi
Daria Nogina
Carl G. de Boer
ResearchOpen Access11 Oct 2024
Nature Biotechnology

Volume: 43, P: 1373-1383
Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection

Cell Painting, gene expression, and chemical structural data are used to examine the differences between mitochondrial toxicants and non-toxicants and enhance the detection of mitotoxic compounds for future drug discovery.

Srijit Seal
Jordi Carreras-Puigvert
Andreas Bender
ResearchOpen Access23 Aug 2022
Communications Biology

Volume: 5, P: 1-15

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Author Correction: Cell Painting: a decade of discovery and innovation in cellular imaging

Cell Painting: a decade of discovery and innovation in cellular imaging

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

A community effort to optimize sequence-based deep learning models of gene regulation

Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection

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