Co-occurrence of immune-mediated inflammatory diseases (IMID) is common in patients with inflammatory bowel disease (IBD). However, to what extent genetic, immune, and microbial factors drive these associations remains elusive. Here, the authors present a multi-modal analysis, integrating genealogical data, genome-wide association data, and microbiota datasets, to disentangle the genetic and microbial contributions to disease co-occurrences.
- Marie Vibeke Vestergaard
- Alonzo Alfaro-Núñez
- Tine Jess
