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Showing 1–13 of 13 results
Advanced filters: Author: Marino Arroyo Clear advanced filters

  • Hydraulic fracturing remodels cell-cell adhesions in physiology and during development. Here, authors combine vesicle experiments and computational modeling to identify the physical principles behind biological fracking.

    • Céline Dinet
    • Alejandro Torres-Sánchez
    • Margarita Staykova
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • Marin-Llaurado and colleagues engineer curved epithelial monolayers of controlled geometry and develop a new technique to map their state of stress. They show that pronounced stress anisotropies influence cell alignment.

    • Ariadna Marín-Llauradó
    • Sohan Kale
    • Xavier Trepat
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • Amphiphysin BAR proteins reshape membranes, but the dynamics of the process remained unexplored. Here, the authors show through experiment and modelling that reshaping depends on the initial template shape, occurs even at low initial curvature, and involves the coexistence of isotropic and nematic states.

    • Anabel-Lise Le Roux
    • Caterina Tozzi
    • Pere Roca-Cusachs
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Theoretical modelling in combination with measurements of tension and shape in epithelial domes of controlled geometry reveals a plateau of tension in tissue that is maintained by heterogeneous strain across cells.

    • Ernest Latorre
    • Sohan Kale
    • Xavier Trepat
    Research
    Nature
    Volume: 563, P: 203-208

  • Measurements in stretched epithelial cell sheets show that epithelial cracks are independent of tension and that epithelial fracture is caused by the hydraulic pressure that builds up in the extracellular matrix during stretching.

    • Laura Casares
    • Romaric Vincent
    • Xavier Trepat
    Research
    Nature Materials
    Volume: 14, P: 343-351

  • Laminin, an important component of the extracellular matrix supporting the epithelium, hinders the typical mechanoresponse of epithelial cells to an increase in substrate stiffness, by protecting the cell nucleus from mechanical deformation.

    • Zanetta Kechagia
    • Pablo Sáez
    • Pere Roca-Cusachs
    ResearchOpen Access
    Nature Materials
    Volume: 22, P: 1409-1420

  • Variations in cell shape must be accommodated by the cell membrane, but how the membrane adjusts to changes in area and volume is not known. Here the authors show that the membrane responds in a nearly instantaneous, purely physical manner involving the flattening or generation of membrane invaginations.

    • Anita Joanna Kosmalska
    • Laura Casares
    • Pere Roca-Cusachs
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-11

  • Lolo et al. show caveolin-1 functions in non-caveolae structures termed dolines. Whereas caveolae respond to high forces over a mechanical threshold, dolines transduce low and medium mechanical forces gradually in a complementary buffering system.

    • Fidel-Nicolás Lolo
    • Nikhil Walani
    • Miguel A. del Pozo
    ResearchOpen Access
    Nature Cell Biology
    Volume: 25, P: 120-133

  • Methods for measuring stress in living cells, tissues and organs are advancing steadily and are increasingly being used for biomedical applications. In this Review, we discuss the concept of tissue stress and the techniques available to measure it in 2D and 3D cell and tissue cultures and in vivo.

    • Manuel Gómez-González
    • Ernest Latorre
    • Xavier Trepat
    Reviews
    Nature Reviews Physics
    Volume: 2, P: 300-317