Mitotic DNA synthesis (MiDAS) has been proposed to utilize break-induced DNA replication, a form of homology-directed DNA repair (HDR). Here, the authors find that core DNA end-resection factors required for HDR, including MRE11, CtIP and BRCA1, and a RecQ family helicase, WRN, are essential for MiDAS.
- Szymon A. Barwacz
- Katrine Lundgaard
- Ying Liu
