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Showing 1–5 of 5 results

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Erratum: Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow

Rachelle W. Johnson
Elizabeth C. Finger
Amato J. Giaccia
Amendments and Corrections27 Oct 2016
Nature Cell Biology

Volume: 18, P: 1260
Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours

A study reporting the results of a clinical trial co-administering the GDF-15-blocking antibody visugromab with the anti-PD-1 antibody nivolumab demonstrates that neutralizing GDF-15 can overcome resistance to immune checkpoint inhibition in cancer.

Ignacio Melero
Maria de Miguel Luken
Eugen Leo
ResearchOpen Access11 Dec 2024
Nature

Volume: 637, P: 1218-1227
Author Correction: Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours

Ignacio Melero
Maria de Miguel Luken
Eugen Leo
Amendments and CorrectionsOpen Access25 Feb 2025
Nature

Volume: 639, P: E18
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pathway.

Eui Jung Moon
Stephano S. Mello
Amato J. Giaccia
ResearchOpen Access14 Jul 2021
Nature Communications

Volume: 12, P: 1-18
Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow

Johnson et al. report that loss of leukaemia inhibitory factor receptor (LIFR) signalling reduces the expression of genes associated with dormancy in metastatic breast cancer cells, and promotes bone marrow colonization and osteoclastogenesis.

Rachelle W. Johnson
Elizabeth C. Finger
Amato J. Giaccia
Research19 Sept 2016
Nature Cell Biology

Volume: 18, P: 1078-1089