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Showing 1–11 of 11 results
Advanced filters: Author: Martin J. Loessner Clear advanced filters
  • Although diagnosis of urinary tract infections has improved through the use of point-of-care molecular technologies, they are however limited by poor specificity and / or sensitivity, and requirement of laboratory resources. In this work, the authors develop a bacteriophage-based diagnostic assay for the detection of prevalent uropathogens.

    • Susanne Meile
    • Jiemin Du
    • Samuel Kilcher
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15
  • Listeria monocytogenes isolates are highly heterogeneous and exhibit different levels of virulence. Here, the authors identify hypervirulent isolates that represent a hybrid sub-lineage of the major lineage II harbouring virulence factors from Listeria ivanovii and wall teichoic acids found in major lineage I.

    • Yuelan Yin
    • Hao Yao
    • Xin’an Jiao
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16
  • Certain bacterial enzymes are packaged within protein chambers that provide a confined environment for their reactions to take place. Ban and colleagues now identify a family of proteins that form nanocompartments, similar to bacterial microcompartments such as the carboxysome, and show that the enzymes within are anchored by their C-terminal extensions to binding sites on the inner surface of the chamber.

    • Markus Sutter
    • Daniel Boehringer
    • Nenad Ban
    Research
    Nature Structural & Molecular Biology
    Volume: 15, P: 939-947
  • The host range of bacteriophages defines their impact on bacterial ecology and diversity. Here, Göller et al. isolate 94 staphylococcal phages from wastewater and determine their host range on 117 staphylococci from 29 species, revealing a predominant multi-species host range and thus great potential for horizontal gene transfer.

    • Pauline C. Göller
    • Tabea Elsener
    • Elena Gómez-Sanz
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17
  • The spatial organization of cell surface receptors is critical for cell signaling and drug action. Here, the authors develop an optoproteomic method for mapping surface protein interactions, revealing cellular responses to antibodies, drugs and viral particles as well as immunosynapse signaling events.

    • Maik Müller
    • Fabienne Gräbnitz
    • Bernd Wollscheid
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17
  • Receptor binding proteins in bacteriophage tails mediate host recognition and thus infectivity. Here Gonzalez et al. identify a receptor binding module shared by different phages that all use receptor binding tail fibers that are transiently capped by their chaperones.

    • Rafael Gonzalez-Serrano
    • Riccardo Rosselli
    • Matthew Dunne
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14
  • Biological shuttles efficiently traffic molecules in cells, inspiring the development of synthetic analogs. Here, the authors create colloidal shuttles that collect, transport, and deliver cargo particles and cells under the control of external electrical and magnetic fields.

    • Ahmet F. Demirörs
    • Fritz Eichenseher
    • André R. Studart
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7
  • Photo-crosslinkable gelatin-based hydrogels hold promise for tissue engineering, but in vivo monitoring challenges hinder their clinical translation. Here, radiopaque, 3D-printable hydrogels with tailored degradation profiles, enable long-term in vivo monitoring and demonstrate potential for adipose tissue engineering by facilitating scaffold colonization and replacement by adipose tissue

    • Kristyna Kolouchova
    • Jana Humajova
    • Sandra Van Vlierberghe
    ResearchOpen Access
    Communications Materials
    Volume: 6, P: 1-11