Nature Search

PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development

Sequence-specific binding of PCBP1 to poly-cytosine DNA enhances cGAS-STING activation and interferon-driven immune responses, revealing a new co-sensing mechanism that restrains breast tumor growth.

Cécile Fréreux
Joseph A. Q. Karam
Philip H. Howe
ResearchOpen Access07 Jan 2026
Communications Biology

P: 1-18
Eighteenth-century genomes show that mixed infections were common at time of peak tuberculosis in Europe

Tuberculosis was once a major killer in Europe. Here the authors use metagenomics to obtain genomic sequences of Mycobacterium tuberculosisfrom human remains from eighteenth-century Hungary, revealing mixed infections within individuals as well as presence of the same strain in two individuals.

Gemma L. Kay
Martin J. Sergeant
Mark J. Pallen
ResearchOpen Access07 Apr 2015
Nature Communications

Volume: 6, P: 1-9
Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Paula Verneri
Camila Vazquez Echegaray
Valeria Levi
ResearchOpen Access23 Mar 2020
Scientific Reports

Volume: 10, P: 1-12
Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates

In-depth morphological and molecular analyses of two haptophyte-infecting viruses reveal intricate virus-host interactions and a viral origin of chromosome proteins of dinoflagellates.

Haina Wang
Lingjie Meng
Ruth-Anne Sandaa
ResearchOpen Access28 Mar 2025
Communications Biology

Volume: 8, P: 1-14
Forb diversity globally is harmed by nutrient enrichment but can be rescued by large mammalian herbivory

In a global grassland dataset, large mammalian herbivores rescued forb cover and diversity from the negative effects of eutrophication.

Rebecca A. Nelson
Lauren L. Sullivan
Susan P. Harrison
ResearchOpen Access15 Mar 2025
Communications Biology

Volume: 8, P: 1-10
The differentiated impacts and constraints of allometry, phylogeny, and environment on the ruminants’ ankle bone

3D geometric morphometrics reveal how phylogeny, allometry, and locomotor adaptations shape the morphology of the ruminant astragalus, highlighting its integrated nature and evolutionary constraints.

Orgebin Pierre
Ilya Dziomber
Mennecart Bastien
ResearchOpen Access18 Mar 2025
Communications Biology

Volume: 8, P: 1-13
Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape

Martin Stortz
Diego M. Presman
Valeria Levi
ResearchOpen Access24 Jul 2017
Scientific Reports

Volume: 7, P: 1-14
Fiddler crabs (Afruca tangeri) detect second-order motion in both intensity and polarization

Fiddler crabs detect second-order motion in both intensity and polarization, a finding that expands our understanding of motion vision in animals and its role in predator detection and behavior.

Samuel P. Smithers
Maisie F. Brett
Nicholas W. Roberts
ResearchOpen Access03 Oct 2024
Communications Biology

Volume: 7, P: 1-8
Compressive stress triggers fibroblasts spreading over cancer cells to generate carcinoma in situ organization

A 3D in vitro model shows that compressive stress is required to generate and maintain a fibroblast capsule around cancer spheroids.

Fabien Bertillot
Laetitia Andrique
Danijela Matic Vignjevic
ResearchOpen Access15 Feb 2024
Communications Biology

Volume: 7, P: 1-12
Disaccharides obtained from carrageenans as potential antitumor agents

Gustavo H. Calvo
Vanina A. Cosenza
Gabriela M. Di Venosa
ResearchOpen Access30 Apr 2019
Scientific Reports

Volume: 9, P: 1-13
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2

Androgen receptor (AR) suppresses DPYSL5, and overexpression of DPYSL5 promotes prostate cancer cell plasticity via EZH2-mediated PRC2 activation, suggesting that the AR/DPYSL5/EZH2/PRC2 axis may act as a driver of treatment-induced neuroendocrine prostate cancer.

Roosa Kaarijärvi
Heidi Kaljunen
Kirsi Ketola
ResearchOpen Access18 Jan 2024
Communications Biology

Volume: 7, P: 1-13
Palaeo-bioinspiration draws on the fossil record to advance innovation

Palaeo-bioinspiration greatly increases the potential of nature-inspired innovation by incorporating extinct biodiversity, which represents 99.9% of all life on earth.

Annabelle Aish
Chris Broeckhoven
Michael Habib
ReviewsOpen Access02 Jun 2025
Communications Biology

Volume: 8, P: 1-12
Transcriptional condensates: a blessing or a curse for gene regulation?

In this Mini Review, the authors discuss the relationship between condensate formation, genome organization, and transcriptional activity, focusing on the experimental evidence behind the role of transcriptional condensates in gene regulation.

Martin Stortz
Diego M. Presman
Valeria Levi
ReviewsOpen Access16 Feb 2024
Communications Biology

Volume: 7, P: 1-10

Search

PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development

Eighteenth-century genomes show that mixed infections were common at time of peak tuberculosis in Europe

Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates

Forb diversity globally is harmed by nutrient enrichment but can be rescued by large mammalian herbivory

The differentiated impacts and constraints of allometry, phylogeny, and environment on the ruminants’ ankle bone

Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape

Fiddler crabs (Afruca tangeri) detect second-order motion in both intensity and polarization

Compressive stress triggers fibroblasts spreading over cancer cells to generate carcinoma in situ organization

Disaccharides obtained from carrageenans as potential antitumor agents

DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2

Palaeo-bioinspiration draws on the fossil record to advance innovation

Transcriptional condensates: a blessing or a curse for gene regulation?

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