In this Review, Fouchier and colleagues explore the evolution, spread and zoonotic risks of highly pathogenic H5 avian influenza viruses. They highlight recent unusual outbreaks, discuss future preparedness strategies from a One Health perspective, and describe countermeasures to mitigate the risks.
- Beatriz Bellido-Martín
- Willemijn F. Rijnink
- Ron A. M. Fouchier