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Sex-specific role of the 5-HT_2A receptor in psilocybin-induced extinction of opioid reward

Here Jaster et al., show a single psilocybin dose produce sex-specific post-acute changes in opioid reward and withdrawal via 5-HT2A receptors in frontal cortex-to–nucleus accumbens circuits, with epigenetic and synaptic changes shaping therapeutic potential.

Alaina M. Jaster
Thomas M. Hadlock
Javier González-Maeso
ResearchOpen Access20 Nov 2025
Nature Communications

Volume: 16, P: 1-25
Author Correction: The Effect of Electronic Cigarette User Modifications and E-liquid Adulteration on the Particle Size Profile of an Aerosolized Product

Haley A. Mulder
Jesse L. Patterson
Michelle R. Peace
Amendments and CorrectionsOpen Access13 Mar 2020
Scientific Reports

Volume: 10, P: 1
The Effect of Electronic Cigarette User Modifications and E-liquid Adulteration on the Particle Size Profile of an Aerosolized Product

Haley A. Mulder
Jesse L. Patterson
Michelle R. Peace
ResearchOpen Access15 Jul 2019
Scientific Reports

Volume: 9, P: 1-8

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Sex-specific role of the 5-HT2A receptor in psilocybin-induced extinction of opioid reward

Author Correction: The Effect of Electronic Cigarette User Modifications and E-liquid Adulteration on the Particle Size Profile of an Aerosolized Product

The Effect of Electronic Cigarette User Modifications and E-liquid Adulteration on the Particle Size Profile of an Aerosolized Product

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Sex-specific role of the 5-HT_2A receptor in psilocybin-induced extinction of opioid reward