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Showing 1–6 of 6 results
Advanced filters: Author: Matthias Budt Clear advanced filters

  • For archival pathogens, like pH1N1 Influenza A virus the causative agent of 1918/19 pandemic, only few whole genome sequences exist. Here, Patrono et al. provide one complete and two partial genomes from Germany and find variation in two sites in the nucleoprotein gene in pandemic samples compared to pre-pandemic samples, that are associated with resistance to host antiviral response, pointing at a possible viral adaptation to humans.

    • Livia V. Patrono
    • Bram Vrancken
    • Sébastien Calvignac-Spencer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • A modelling approach predicts SARS-CoV-2 variant dynamics on the basis of immunity and cross-neutralization, which was shaped by a region’s SARS-CoV-2 infection history.

    • N. Alexia Raharinirina
    • Nils Gubela
    • Max von Kleist
    ResearchOpen Access
    Nature
    Volume: 639, P: 196-204

  • Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA structure features for regulation of M segment RNA splicing.

    • Boris Bogdanow
    • Xi Wang
    • Matthias Selbach
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • In this study, the authors report that bat H9N2 influenza A virus replicates and transmits in ferrets, efficiently infects human lung explant cultures, evades MxA antiviral activity in mice, and has low antigenic similarity to seasonal N2, meeting pre-pandemic criteria.

    • Nico Joel Halwe
    • Lea Hamberger
    • Martin Beer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-8

  • Oh, Hölzer et al., discuss the multidisciplinary approach used for monitoring the genomic and virological evolution of SARS-CoV-2 during the COVID-19 pandemic and its implications on public health in Germany. They emphasize the need for continuous surveillance and adaptation of public health strategies to address evolving viral threats.

    • Djin-Ye Oh
    • Martin Hölzer
    • Wiep van der Toorn
    ReviewsOpen Access
    Communications Medicine
    Volume: 5, P: 1-22