Following epithelial-mesenchymal transition, avian trunk neural crest cell polarity determines directional migration but how this is established is unclear. Here, the authors find that the RhoGAP, Deleted in liver cancer 1, is asymmetrically localized in the cytoplasm, governing neural crest migratory polarization.
- Jessica Aijia Liu
- Yanxia Rao
- Martin Cheung