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Showing 1–21 of 21 results
Advanced filters: Author: Mehrdad Jazayeri Clear advanced filters

  • Mental simulation is key to flexible inference and other cognitive functions. Here the authors show that the frontal cortex recursively updates the internal state of objects over short time intervals, supporting the simulation hypothesis.

    • Rishi Rajalingham
    • Hansem Sohn
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Humans and monkeys integrated experiential and observational evidence during a two-player task, and the anterior cingulate cortex combined the information sources into a unified neural belief representation that explains behavioural asymmetries.

    • Ruidong Chen
    • Setayesh Radkani
    • Mehrdad Jazayeri
    Research
    Nature
    Volume: 650, P: 681-689

  • We can flexibly coordinate our movements with external stimuli, but no circuit-level model exists to explain this ability. Inspired by fundamental concepts in control theory, the authors construct a modular neural circuit that captures human behavior in a wide range of temporal coordination tasks.

    • Seth W. Egger
    • Nhat M. Le
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Measurements of activity in the entorhinal cortex of monkeys indicate that the recruitment of a cognitive map is a key part of mental navigation, and that cognitive maps can support behavior in the absence of external sensory input.

    • Sujaya Neupane
    • Ila Fiete
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature
    Volume: 630, P: 704-711

  • Perceptual illusions are thought to arise from the way sensory signals are encoded, but this details how one could result from the way the brain decodes sensory information. Different pools of neurons contribute the most information in different motion discrimination tasks, and human observers display perceptual biases in the tasks that could correspond to the different neural decoding strategies.

    • Mehrdad Jazayeri
    • J. Anthony Movshon
    Research
    Nature
    Volume: 446, P: 912-915

  • Optogenetic manipulations of behavior in primates have largely been unsuccessful. Here, the authors report that monkeys reliably shift their gaze toward the receptive field of optically driven channelrhodopsin-2–expressing V1 neurons.

    • Mehrdad Jazayeri
    • Zachary Lindbloom-Brown
    • Gregory D Horwitz
    Research
    Nature Neuroscience
    Volume: 15, P: 1368-1370

  • The ability to infer the dynamics of physical objects is hypothesized to rely on running simulations of mental models. Here, the authors test this hypothesis by comparing human and monkey behavior to recurrent neural network models in a physical inference task.

    • Rishi Rajalingham
    • Aída Piccato
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Control of movements can be understood in terms of the interplay between a controller, a simulator and an estimator. Egger et. al. show that cortical neurons establish the same building blocks to control cognitive states in the absence of movement.

    • Seth W. Egger
    • Evan D. Remington
    • Mehrdad Jazayeri
    Research
    Nature Neuroscience
    Volume: 22, P: 1871-1882

  • Graf et al. examine how information can be decoded from the pattern of population activity in primary visual cortex neurons. They find that the structure of neuronal response distributions, including their correlated variability, contains critical information for sensory decoding.

    • Arnulf B A Graf
    • Adam Kohn
    • J Anthony Movshon
    Research
    Nature Neuroscience
    Volume: 14, P: 239-245

  • Humans compensate for sensory noise by biasing sensory estimates toward prior expectations, as predicted by models of Bayesian inference. Here, the authors show that humans perform ‘late inference’ downstream of sensory processing to mitigate the effects of noisy internal mental computations.

    • Evan D. Remington
    • Tiffany V. Parks
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • The authors find that a person's estimate of a time interval exhibits biases that depend on both its duration and the distribution from which it is drawn. This behavioral pattern could be described using a Bayesian model. These findings suggest that internal timing mechanisms can adapt to the temporal statistics of the environment to minimize uncertainty.

    • Mehrdad Jazayeri
    • Michael N Shadlen
    Research
    Nature Neuroscience
    Volume: 13, P: 1020-1026

  • Human timing behavior is biased towards previously encountered intervals and is predicted by Bayesian models. Here, the authors develop a computational model based in properties of the cerebellum to show how we might encode time estimates based on prior experience.

    • Devika Narain
    • Evan D. Remington
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • Humans can deliberately control the timing of their actions but the neural mechanisms underlying such control are largely unknown. In this article, Wang, Narain and their colleagues report that such flexibility emerges in rhesus monkeys from the ability of their brain to flexibly control the speed at which cortical responses unfold in time.

    • Jing Wang
    • Devika Narain
    • Mehrdad Jazayeri
    ResearchOpen Access
    Nature Neuroscience
    Volume: 21, P: 102-110