Catalytic asymmetric dearomatizations of electronically unbiased naphthalenes remains a long-standing challenge in organic chemistry. Here, the authors describe a silver-mediated enantioselective aza-electrophilic dearomatization approach that couples readily accessible vinylnaphthalenes in conjunction with azodicarboxylates to afford chiral polyheterocycles via formal [4 + 2] cycloaddition reactions.
- Jun Liu
- Haina Liu
- Hongyu Wang
