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Correction: Corrigendum: Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

Daniel R Getts
Aaron J Martin
Stephen D Miller
Amendments and Corrections10 Jun 2013
Nature Biotechnology

Volume: 31, P: 565
Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

Andrew S. Mendiola
Jae Kyu Ryu
Katerina Akassoglou
Amendments and Corrections13 Jul 2020
Nature Immunology

Volume: 21, P: 1135
Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling and cloud-native open-source tools

Lightning Pose is an efficient pose estimation approach that requires few labeled training data owing to its semi-supervised learning strategy and ensembling.

Dan Biderman
Matthew R. Whiteway
Liam Paninski
Research25 Jun 2024
Nature Methods

Volume: 21, P: 1316-1328
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

Oxidative stress can promote neurodegeneration. Akassoglou and colleagues describe Tox-seq, a functional single-cell RNA sequencing method to identify oxidative stress transcriptional signatures in CNS-resident cells. Tox-seq identified coagulation and glutathione-redox pathway genes that are coupled to oxidative stress and that could be targeted by the glutathione-regulating small molecule acivicin.

Andrew S. Mendiola
Jae Kyu Ryu
Katerina Akassoglou
Research13 Apr 2020
Nature Immunology

Volume: 21, P: 513-524
Dichotic Listening before and after Fluoxetine Treatment for Major Depression: Relations of Laterality to Therapeutic Response

Gerard E Bruder
Michael W Otto
Frederic M Quitkin
Research01 Aug 1996
Neuropsychopharmacology

Volume: 15, P: 171-179
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Inclusions containing TDP43 are linked to pathologies in several neurodegenerative diseases such as ALS and FTD. Pathogenic TDP43 mutations are now found to shorten the protein's half-life in individual neurons. Stimulating autophagy with inhibitors improves TDP43 clearance and localization.

Sami J Barmada
Andrea Serio
Steven Finkbeiner
Research29 Jun 2014
Nature Chemical Biology

Volume: 10, P: 677-685
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

Microparticles coated with encephalitogenic peptides are effective at treating multiple sclerosis in a mouse model.

Daniel R Getts
Aaron J Martin
Stephen D Miller
Research18 Nov 2012
Nature Biotechnology

Volume: 30, P: 1217-1224
Detection of splice isoforms and rare intermediates using multiplexed primer extension sequencing

MPE-seq uses pools of reverse-transcription primers to facilitate enrichment of splice isoforms and pre-mRNA splicing intermediates.

Hansen Xu
Benjamin J. Fair
Jeffrey A. Pleiss
Research20 Dec 2018
Nature Methods

Volume: 16, P: 55-58
SR protein kinases promote splicing of nonconsensus introns

Chemical genetics, proteomics and biochemistry are used to probe the functions of SR protein kinases. An identified target of Dsk1 is spliceosomal protein Bpb1 (SF1), whose phosphorylation increased its binding to introns with nonconsensus splice sites.

Jesse J Lipp
Michael C Marvin
Christine Guthrie
Research13 Jul 2015
Nature Structural & Molecular Biology

Volume: 22, P: 611-617
Blunted Serotonergic Responsivity in Depressed Inpatients

J John Mann
P Anne McBride
John Keilp
Research01 Aug 1995
Neuropsychopharmacology

Volume: 13, P: 53-64

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