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The authors develop textile electronic substrates with tailored stiffness and interfacial affinities by selective and controllable laser-matter interaction, addressing the mechanical mismatch between hybrid electronics and elastic textiles.

Newly developed mouse models that enable cell-specific analyses of proteostasis dynamics across the lifespan of the mice reveal key aspects of neuronal proteostasis with ageing.

Perception can occur in the absence of report. Here, the authors use intracranial recordings to show that sequential sampling of sensory evidence in the ventral visual cortex supports perception beyond report.

This study reveals how controlling the contact angle enables clean, residue-free peeling of gallium-based liquid metals without chemical treatments, offering a simple method for precise and contamination-free patterning of liquid metal structures.

Bacteriocins include antimicrobial peptides (AMPs) that often disrupt the cytoplasmic membrane. Here, the authors describe TMcin (transmembrane helix-containing bacteriocin), a class of AMPs that forms large, structured pores in the target membrane.

Human papillomavirus (HPV)-associated oropharyngeal cancer is increasing but the natural history of oral HPV infection is not well understood. Here, the authors investigate clearance of oncogenic oral HPV infection in a cohort of men from the US, Brazil, and Mexico.

Techniques for shape-controlling of hydrogels, that is, crosslinked networks of polymers, could make possible various biomimetic applications. Palleau et al.propose a strategy to pattern three-dimensional hydrogels using electric potential, which allows directed bending and fast controllable actuation.

A wearable device measures parenchymal resistance and its dynamic relationship with sleep MRI measures of glymphatic function, EEG features and cardiovascular parameters in humans.

Although there are many reports on the development of devices for terahertz signal processing, the possibility of electrical control of the functionality remains elusive. Here, the authors use electrically actuated liquid metal components incorporated into terahertz waveguides for controlling power flow and for frequency filtering.

Eutrophication and chlorophyll-rich algal blooms occurred at high concentrations of the thermoplastic polyurethane, but only occasionally with bioplastics, suggests a three-month experiment exposing plankton in experimental ponds.

Unilateral inactivation of the superior colliculus in monkeys reveals that a brainstem structure plays a causal role in how evidence is computed for decisions, a process usually attributed to the forebrain.

A plasmonic printing technology is developed to enable rapid, room-temperature, scalable fabrication of all-metal oxide thin-film transistors and circuits.

The Hsp90 chaperone cycle is influenced by multiple phosphorylation events but their regulatory functions are poorly understood. Here, the authors show that phosphorylation and unfolding of cochaperone Cdc37 tailors the Hsp90 chaperone cycle by recruiting kinases that promote distinct phosphorylation patterns.

Multinational analysis of oral human papillomavirus infection incidence and associated factors in 3,137 men reveals infection risk is maintained throughout lifetime, with implications for vaccination strategies.

Free-standing metallic structures with high conductivities and aspect ratios can be 3D printed from Field’s metal using a direct ink writing method that avoids using external pressure to drive ink through the nozzle.

The South Asian summer monsoon has an impact on over one billion people. This study applies statistical techniques to precipitation observations (over the period 1951–2011) and finds significant increases in daily precipitation variability, the frequency of dry spells and the intensity of wet spells, whereas dry spell intensity decreases.

A study reports the distribution, replication and persistence of SARS-CoV-2 throughout the human body including in the brain at autopsy from acute infection to more than seven months following symptom onset.

Liquid metal-based infrared-modulating materials and systems have been developed to regulate the infrared reflection with multiple modes, which can be used for infrared camouflage, programmable infrared encryption, and infrared painting/writing.

Asthma is associated with mucus overproduction; however, the immunological consequences of excess mucus remain poorly understood. Here the authors show that formation of airway plugs by mucus promotes airway hypersensitivity, while deletion of mucous component Muc5acablates it independently of inflammation.

Liquid metals that have enormous surface tension are difficult to pattern into films. Here, authors report the spontaneous and selective wetting of a gallium-based liquid metal, which is induced by imbibition on a micro-structured metallized substrate.

Positively charged anodes should short circuit when they are brought into contact with a cathode. The authors demonstrate that a liquid-metal anode can naturally flow toward the cathode, completely surround it and ultimately transfer to the cathode without short circuiting in an electrochemical cell.

Solvating polar polymers with ionic liquids at appropriate concentrations can produce a unique class of materials called glassy gels with desirable properties of both glasses and gels.

A microglial state, featuring lipid droplets and secretion of neurotoxic factors, is shown to be most prominent in people with Alzheimer’s disease who have the APOE4 genotype.

Lipopeptides secreted by Bacillus bacteria block quorum sensing by Staphylococcus aureus and thereby inhibit the growth of this opportunistic pathogen in the gut, suggesting why people in rural Thailand who are colonized by Bacillus are not also colonized by S. aureus.

The use of inorganic carriers for drug delivery is often limited by toxicity and persistence of inorganic species in the body. Here, the authors report the use of nanocarriers with a liquid-phase eutectic gallium-indium core capable of delivering doxorubicin and subsequently fusing and degrading under mildly acidic conditions.

Blood plasma protein data was combined with machine learning models for a simple method to determine differences in organ-specific aging; the study provides a basis for the prediction of diseases and aging effects using plasma proteomics.

High-resolution cryo-EM structures of S. aureus ABC transporter PmtCD in apo and ADP-bound states in multiple membrane mimetics define a large intramembrane lumen, adding insight to the export of virulence peptides during staphylococcal infections.

Peptides that disrupt Ca²⁺-triggered membrane fusion may enable the therapeutic modulation of mucin secretory pathways.

One of the key challenges 2D materials still face is their uniform wafer-scale deposition. Here, the authors present a deposition method for post-transition metal dichalcogenides, based on transformation of an ultra-thin oxide layer on the surface of liquid elemental gallium onto an oxide-coated substrate.

Designing bio-inspired computational features in soft systems without centralized processing remains challenging. Here, the authors propose a passive display based on thermochromic elastomers by leveraging Joule heating of embedded liquid metal wires by changing geometry in response to deformation.

Plasma from voluntarily running mice reduces baseline expression of neuroinflammatory genes and experimentally induced brain inflammation when infused into sedentary mice.

Two monomers with distinct solubility of their corresponding polymers in an ionic liquid enable tuning of the microstructure of the copolymers during their polymerization. Thus, energy dissipative and elastic molecular domains are created, resulting in highly tough and stretchable ionogels.

The genomic profiling of tumours has not been widely adopted in the clinic due to technical and practical hurdles. Here, the authors develop PGDx elio tissue complete, a scalable, standardised and FDA-cleared test comprising a targeted gene panel and automated machine-learning analysis, which detects clinically relevant sequence biomarkers in cancer samples.

CD22 inhibits microglial phagocytosis in the ageing brain, and treatment with a CD22-blocking antibody restores microglial homeostasis and cognitive function in ageing mice.

Liquid metal-filled elastic composites for strain sensing devices exhibit reduced conductivity under strain, which limits their usefulness. Here, the authors report a positive piezoconductive effect in liquid metal-filled magnetorheological elastomers and illustrate proof-of concept applications.

While CO₂ reduction proves an appealing means to convert greenhouse emissions to high-value products, there are few materials capable of such a conversion. Here, the authors demonstrate a liquid-metal electrocatalyst to convert CO₂ directly into solid carbon that can be used as capacitor electrodes.

A plant-inspired approach can be used to print hydrogels that dynamically change shape on immersion in water in order to yield prescribed complex structures.

Fgf17 in young CSF boosts oligodendrocyte progenitor cell proliferation and differentiation in the aged hippocampus, improving memory function.

Bulk RNA sequencing of organs and plasma proteomics at different ages across the mouse lifespan is integrated with data from the Tabula Muris Senis, a transcriptomic atlas of ageing mouse tissues, to describe organ-specific changes in gene expression during ageing.