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Showing 1–4 of 4 results
Advanced filters: Author: Michael Fähling Clear advanced filters
  • T-cell–mediated rejection (TCMR) remains a major cause of kidney transplant failure with incompletely understood mechanisms. Here the authors use single-nucleus RNA sequencing, spatial transcriptomics and immunofluorescence to show that injured kidney epithelial cell states associate with poor transplant outcomes after T-cell–mediated rejection.

    • Anna Maria Pfefferkorn
    • Lorenz Jahn
    • Christian Hinze
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-19
  • Contrast agents can damage the kidney through several mechanisms. Here, the authors discuss current understanding of the incidence and pathophysiology of contrast-induced acute kidney injury and highlight the need to consider individual patient risk factors when considering prevention strategies.

    • Michael Fähling
    • Erdmann Seeliger
    • Pontus B. Persson
    Reviews
    Nature Reviews Nephrology
    Volume: 13, P: 169-180