We revealed that the pathogenesis of mTORi-induced lung injury may be involved in alveolar epithelial injury via lipid metabolic stress associated with downregulated PPAR-γ expression. Focusing on the relationship between lipid metabolic stress and alveolar epithelial injury represents a potentially novel approach to the study of pulmonary damage.
- Nariaki Kokuho
- Yasuhiro Terasaki
- Akira Shimizu
