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Advanced filters: Author: Milan Fábry Clear advanced filters

Molecular insight into 5′ RNA capping with Np_nNs by bacterial RNA polymerase

Using cryo-electron microscopy technologies, Serianni and Škerlová et al. reveal how Np_nNs initiate bacterial transcription as noncanonical RNA caps by showing one nucleobase pairing with the template in canonical mode while the other pairs in reverse Watson–Crick mode.

Valentina M. Serianni
Jana Škerlová
Hana Cahova
ResearchOpen Access09 Jan 2026
Nature Chemical Biology

P: 1-8
Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

LEDGF/p75, a protein involved in HIV integration and leukaemia, interacts with various cellular proteins via its integrase binding domain (IBD). Here, the authors show that the interaction is mediated by an intrinsically disordered IBD-binding motif (IBM) on all known cellular partners of LEDGF/p75.

Petr Tesina
Kateřina Čermáková
Pavlína Řezáčová
Research06 Aug 2015
Nature Communications

Volume: 6, P: 1-14
N-Glycosylation can selectively block or foster different receptor–ligand binding modes

Joni Vuorio
Jana Škerlová
Hector Martinez-Seara
ResearchOpen Access04 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation

Aleš Hnízda
Milan Fábry
Václav Veverka
Research25 Feb 2018
Leukemia

Volume: 32, P: 1393-1403

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