Nature Search

Feasibility and utility of a tablet-based digital neurocognitive assessment following radiosurgery for brain metastases

Eyub Y. Akdemir
Joseph DiStefano
Rupesh Kotecha
ResearchOpen Access14 Apr 2026
Scientific Reports

P: 1-9
Gangliogliomas—what is the appropriate management strategy?

Ganglioglioma is a rare form of low-grade glioma that mainly affects children and young adults. The low incidence of this tumor has precluded prospective studies of available treatment strategies. A large retrospective study has now examined the effectiveness of these strategies, specifically the influence of postoperative radiotherapy on patient outcome.

Minesh P. Mehta
News & Views01 Apr 2010
Nature Reviews Neurology

Volume: 6, P: 190-191
Gabapentinoids confer survival benefit in human glioblastoma

In preclinical studies, the FDA approved TSP-1 antagonist gabapentin has been shown to disrupt neuronal-glioma interactions, slowing glioblastoma progression. Here, authors report a retrospective cohort study demonstrating a survival benefit associated with gabapentin in patients with newly diagnosed glioblastoma.

Joshua D. Bernstock
Mulki Mehari
Shawn L. Hervey-Jumper
ResearchOpen Access15 May 2025
Nature Communications

Volume: 16, P: 1-6
Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses

A risk score based on a 34-gene signature for outcome prediction in meningioma was developed and validated in large multi-institutional cohorts and showed better performance in discriminating postoperative menignioma outcomes compared with existing meningioma classification systems.

William C. Chen
Abrar Choudhury
David R. Raleigh
Research09 Nov 2023
Nature Medicine

Volume: 29, P: 3067-3076
Factors associated with unplanned readmissions and costs following resection of brain metastases in the United States

Raees Tonse
Alexandra Townsend
Rupesh Kotecha
ResearchOpen Access12 Nov 2021
Scientific Reports

Volume: 11, P: 1-8
Hospitalization rates for complications due to systemic therapy in the United States

Anshul Saxena
Muni Rubens
Rupesh Kotecha
ResearchOpen Access01 Apr 2021
Scientific Reports

Volume: 11, P: 1-7
Hospitalization rates from radiotherapy complications in the United States

Raees Tonse
Venkataraghavan Ramamoorthy
Rupesh Kotecha
ResearchOpen Access14 Mar 2022
Scientific Reports

Volume: 12, P: 1-7
Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

A breakthrough in drug discovery for glioblastoma requires serial collection of tissue from the central nervous system via window of opportunity trials

Kirit Singh
Kelly M. Hotchkiss
Mustafa Khasraw
Comments & Opinion24 Jul 2023
Nature Medicine

Volume: 29, P: 2402-2405
Proton therapy for paediatric CNS tumours — improving treatment-related outcomes

In modern X-ray therapy, healthy brain tissue that surrounds a CNS tumour receives low to medium dose irradiation, which has important long-term adverse effects such as cognitive toxicity, endocrinopathy, hearing loss and vasculopathic effects. Prolonged long-term survival in certain paediatric CNS tumours call for more attention in avoiding the long-term sequelae of radiotherapy. This Review discusses how proton therapy improves dose distribution and can help reduce long-term toxicities.

Vinai Gondi
Torunn I. Yock
Minesh P. Mehta
Reviews20 May 2016
Nature Reviews Neurology

Volume: 12, P: 334-345
Evaluation of the impact of pre-operative stereotactic radiotherapy on the acute changes in histopathologic and immune marker profiles of brain metastases

Rupesh Kotecha
Raees Tonse
Michael W. McDermott
ResearchOpen Access16 Mar 2022
Scientific Reports

Volume: 12, P: 1-9
Initial feasibility cohort of temporally modulated pulsed proton re-irradiation (TMPPR) for recurrent high-grade intracranial malignancies

Alonso La Rosa
Zachary Fellows
Rupesh Kotecha
ResearchOpen Access04 Nov 2024
Scientific Reports

Volume: 14, P: 1-12

Search

Filter By:

Search

Quick links