Nature Search

Lipid metabolism drives dietary effects on T cell ferroptosis and immunity

The susceptibility of mouse and human T cells to ferroptosis is determined by the balance of systemic polyunsaturated and monounsaturated fatty acids, highlighting a key role for lipid metabolism and dietary composition in regulating T cell function.

Naiqi Wang
Zhian Chen
Di Yu
Research04 Mar 2026
Nature

P: 1-12
Emulating human-like adaptive vision for efficient and flexible machine visual perception

A deep learning approach, AdaptiveNN, shifts machine vision models from passive to active to mimic human-like perception. The method achieves inference costs that are up to 28-times lower without accuracy loss, while showcasing online-adaptable and interpretable behaviours.

Yulin Wang
Yang Yue
Gao Huang
Research06 Nov 2025
Nature Machine Intelligence

Volume: 7, P: 1804-1822
Study on the evolution law of failure depth of large mining height and ultra-wide working surface

Wenqiang Wang
Zhenhua Li
Mengsen Liu
ResearchOpen Access02 Jan 2026
Scientific Reports

Volume: 16, P: 1-15
Experimental study on the structural failure characteristics and load-bearing mechanism of anchored fractured rock mass

Mengsen Liu
Zhenhua Li
Jianhang Shi
ResearchOpen Access03 Feb 2026
Scientific Reports

Volume: 16, P: 1-14
A 10 m maize, rice and soybean yield dataset from 2016 to 2021 in Northeast China

Fei Teng
Minglei Wang
Xiangming Xiao
ResearchOpen Access03 Feb 2026
Scientific Data

Volume: 13, P: 1-12
PET/CT based cross-modal deep learning signature to predict occult nodal metastasis in lung cancer

Occult node metastasis is a key staging component of non-small cell lung cancer. Here, the authors use deep learning to improve diagnosis of lymph node metastasis from PET and CT radiomics.

Yifan Zhong
Chuang Cai
Yunlang She
ResearchOpen Access18 Nov 2023
Nature Communications

Volume: 14, P: 1-14
Paraventricular hypothalamic RUVBL2 neurons suppress appetite by enhancing excitatory synaptic transmission in distinct neurocircuits

The paraventricular hypothalamus (PVH) exerts an indispensable role in body weight control. Here, authors demonstrate the role of PVH RUVBL2 in suppressing food intake and reveal two anorexigenic circuits of PVHRUVBL2 → ARCPOMC and PVHRUVBL2 → DMH.

Mingming Xing
Yang Li
Xiangyang Xie
ResearchOpen Access16 Oct 2024
Nature Communications

Volume: 15, P: 1-21
MyoD is a 3D genome structure organizer for muscle cell identity

Pioneer transcription factors (TFs) have been proposed to act as protein anchors to orchestrate cell type-specific 3D genome architecture. MyoD is a pioneer TF for myogenic lineage specification. Here the authors provide further support for the role of MyoD in 3D genome architecture in muscle stem cells by comparing MyoD knockout and wild-type mice.

Ruiting Wang
Fengling Chen
Dahai Zhu
ResearchOpen Access11 Jan 2022
Nature Communications

Volume: 13, P: 1-17
3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia

The non-coding genome of T-ALL has not been extensively studied. Here, the authors conduct RNA-seq, ATAC-seq and Hi-C seq analyses and find that T-ALL associated neo-loops may regulate key transcription factors including HOXA13; the aberrant expression of which is associated with poor prognosis.

Lu Yang
Fengling Chen
Hong Wu
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-12
SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment

SEAM is a platform for the analysis of high-resolution secondary ion mass spectrometry imaging that allows spatially resolved nuclear metabolomic profiling at the single-cell level.

Zhiyuan Yuan
Qiming Zhou
Michael Q. Zhang
Research04 Oct 2021
Nature Methods

Volume: 18, P: 1223-1232
Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implantation response.

Shaopeng Zhang
Tianzhi Chen
Jianyong Han
ResearchOpen Access30 Jan 2019
Nature Communications

Volume: 10, P: 1-17
SOTIP is a versatile method for microenvironment modeling with spatial omics data

Methods that analyse heterogeneity and compare tissue microenvironments using spatial omics data are challenging to develop. Here, the authors present SOTIP, a method that can perform spatial heterogeneity, spatial domain, and differential microenvironment analyses across multiple spatial omics modalities.

Zhiyuan Yuan
Yisi Li
Michael Q. Zhang
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-19
Wheat redistribution in Huang-Huai-Hai, China, could reduce groundwater depletion and environmental footprints without compromising production

Strategic redistribution of wheat in China’s Huang-Huai-Hai region could significantly reduce environmental impacts and groundwater depletion by improving water and nitrogen use efficiency without decreasing wheat production, according to optimization models

Wenjiao Shi
Minglei Wang
Xiaoqing Wang
ResearchOpen Access16 Jul 2024
Communications Earth & Environment

Volume: 5, P: 1-14
BRD4-targeting PROTAC as a unique tool to study biomolecular condensates

Yi Shi
Yuan Liao
Yu Rao
ResearchOpen Access09 May 2023
Cell Discovery

Volume: 9, P: 1-13
Nearly complete redirection of insertion-type indel into recombination enhances knock-in and facilitates endogenous biomolecular condensate analysis

Minglei Huang
Jingjing Fu
Yinqing Li
Correspondence29 Oct 2025
Cell Research

Volume: 35, P: 1079-1082
The annual dynamic dataset of high-resolution crop water use in China from 1991 to 2019

Minglei Wang
Wenjiao Shi
ResearchOpen Access18 Dec 2024
Scientific Data

Volume: 11, P: 1-12

Search

Lipid metabolism drives dietary effects on T cell ferroptosis and immunity

Emulating human-like adaptive vision for efficient and flexible machine visual perception

Study on the evolution law of failure depth of large mining height and ultra-wide working surface

Experimental study on the structural failure characteristics and load-bearing mechanism of anchored fractured rock mass

A 10 m maize, rice and soybean yield dataset from 2016 to 2021 in Northeast China

PET/CT based cross-modal deep learning signature to predict occult nodal metastasis in lung cancer

Paraventricular hypothalamic RUVBL2 neurons suppress appetite by enhancing excitatory synaptic transmission in distinct neurocircuits

MyoD is a 3D genome structure organizer for muscle cell identity

3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia

SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

SOTIP is a versatile method for microenvironment modeling with spatial omics data

Wheat redistribution in Huang-Huai-Hai, China, could reduce groundwater depletion and environmental footprints without compromising production

BRD4-targeting PROTAC as a unique tool to study biomolecular condensates

Nearly complete redirection of insertion-type indel into recombination enhances knock-in and facilitates endogenous biomolecular condensate analysis

The annual dynamic dataset of high-resolution crop water use in China from 1991 to 2019

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