Nature Search

Making long-haul large-capacity 400G optical network a reality

Long-haul large-capacity 400G optical transmission over 1,500 km is possible through advanced fibre-optic systems. This Review provides a holistic view of the signal modulation, spectrum plans, optical components and optical-layer infrastructure necessary to achieve those networks.

Han Li
Dong Wang
Dawei Ge
Reviews01 Apr 2026
Nature Reviews Electrical Engineering

P: 1-12
Engineered bacterial therapy suppresses Enterohemorrhagic Escherichia coli through metabolic competition and virulence silencing

Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen where therapeutic antibiotic treatment can release toxins and disrupt gut microbiota. Here the authors demonstrate a therapeutic strategy where an engineered Escherichia coli Nissle 1917 limits the glucuronic acid utilization by EHEC.

Guozhen Ma
Ruiying Liu
Yutao Liu
ResearchOpen Access03 Feb 2026
Nature Communications

Volume: 17, P: 1-18
Deep learning-enabled ultra-broadband terahertz high-dimensional photodetector

Simultaneously capturing polarization and frequency is challenging. This work develops a metasurface-based intelligent photodetector, which can detect arbitrary polarization and frequency within 0.3-1.1 THz with a total error smaller than 5.1%.

Zong-Kun Zhang
Teng Zhang
Ming-Yao Xia
ResearchOpen Access30 Aug 2025
Nature Communications

Volume: 16, P: 1-11
A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

Many thrombolytic agents depend on plasminogen, leading to D-dimer accumulation. Here, Tang et al. report a plasminogen-independent thrombolytic enzyme that degrades blood clots and D-dimer without plasminogen.

Mingqing Tang
Guoxing Ma
Ruian Xu
ResearchOpen Access24 Apr 2025
Nature Communications

Volume: 16, P: 1-19
Borate driven heterogeneous networks for porous elastomers with improved tribological and mechanical performances

Porous polydimethylsiloxane elastomers produced by phase separation methods often suffer from limited tribological and mechanical properties. Here, the authors describe the synthesis of porous elastomers with borate driven heterogeneous networks, improving tribological properties, with controllable pore structure and mechanical performance.

Yuhao Wu
Liguo Qin
Guangneng Dong
ResearchOpen Access17 Dec 2025
Nature Communications

Volume: 16, P: 1-13
Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases

Loneliness was found to be linked to increased risk for 30 out of 56 diseases in a UK Biobank study. However, genetic analyses show that loneliness likely causes only six diseases. These findings suggest that loneliness is more a potential surrogate marker than a direct cause for most diseases.

Yannis Yan Liang
Mingqing Zhou
Jihui Zhang
ResearchOpen Access16 Sept 2024
Nature Human Behaviour

Volume: 8, P: 2209-2221
High expression of microRNA-183/182/96 cluster as a prognostic biomarker for breast cancer

Cailu Song
Lijuan Zhang
Xiaoming Xie
ResearchOpen Access13 Apr 2016
Scientific Reports

Volume: 6, P: 1-8
Prediction of super-large diameter shield attitude based on LSTM-Transformer

Linfabao Dai
Wenming Chen
Zhengzheng Wang
ResearchOpen Access05 May 2025
Scientific Reports

Volume: 15, P: 1-22
Ginsenoside Rd protects against acute liver injury by regulating the autophagy NLRP3 inflammasome pathway

Xiaomei Zhong
Yibin Sun
Jianyuan Song
ResearchOpen Access28 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells

Mingqing Wu
Lu Sheng
Yang Li
Research27 Mar 2019
Oncogene

Volume: 38, P: 5425-5439
Combined Inhibition of PI3K and STAT3 signaling effectively inhibits bladder cancer growth

Weidong Peng
Haojie Zhang
Yang Li
ResearchOpen Access27 Jul 2024
Oncogenesis

Volume: 13, P: 1-12
The m⁶A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network

Maosheng Cheng
Lu Sheng
Yang Li
Research18 Jan 2019
Oncogene

Volume: 38, P: 3667-3680
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity

Zhexin Ni
Yangshuo Li
Chaoqin Yu
ResearchOpen Access04 Jul 2022
Cell Death & Disease

Volume: 13, P: 1-15
Integrated genomic analysis reveals regulatory pathways and dynamic landscapes of the tRNA transcriptome

Zefang Sun
Jia Tan
Quanyuan He
ResearchOpen Access04 Mar 2021
Scientific Reports

Volume: 11, P: 1-16

Search

Making long-haul large-capacity 400G optical network a reality

Engineered bacterial therapy suppresses Enterohemorrhagic Escherichia coli through metabolic competition and virulence silencing

Deep learning-enabled ultra-broadband terahertz high-dimensional photodetector

A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus

Borate driven heterogeneous networks for porous elastomers with improved tribological and mechanical performances

Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases

High expression of microRNA-183/182/96 cluster as a prognostic biomarker for breast cancer

Prediction of super-large diameter shield attitude based on LSTM-Transformer

Ginsenoside Rd protects against acute liver injury by regulating the autophagy NLRP3 inflammasome pathway

Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells

Combined Inhibition of PI3K and STAT3 signaling effectively inhibits bladder cancer growth

The m⁶A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network

Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity

Integrated genomic analysis reveals regulatory pathways and dynamic landscapes of the tRNA transcriptome

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