Solid tumours are less responsive to immunotherapies than haematological tumours due to specific biological differences. In this paper the authors propose a strategy to decorate the cell membrane of solid tumours with a protein typically present on haematological tumour cells that promotes phagocytosis of cancer cells, and show that this results in an increased immunotherapy efficacy in animal models of solid tumours.
- Yifei Lu
- Kristin Huntoon
- Wen Jiang