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Showing 1–3 of 3 results
Advanced filters: Author: Mohammad Balood Clear advanced filters

  • Melanoma cells interact with pain-mediating sensory neurons by increasing their release of the neuropeptide CGRP, which increases the exhaustion of CD8+ T cells and thus promotes the survival of cancer cells.

    • Mohammad Balood
    • Maryam Ahmadi
    • Sebastien Talbot
    ResearchOpen Access
    Nature
    Volume: 611, P: 405-412

  • Perineural invasion and cancer-induced nerve injury of tumour-associated nerves are associated with poor response to anti-PD-1 therapy, which can be reversed by combining anti-PD-1 therapy with anti-inflammatory interventions.

    • Erez N. Baruch
    • Frederico O. Gleber-Netto
    • Moran Amit
    ResearchOpen Access
    Nature
    Volume: 646, P: 462-473

  • CBFA2T3-GLIS2 is a fusion oncogene found in a subset of pediatric acute megakaryoblastic leukemia associated with a poor prognosis. Here, Garfinkle et al. map the gene regulatory network of CBFA2T3-GLIS2 using a humanized murine model and identify signaling pathways required for leukemogenesis.

    • Elizabeth A. R. Garfinkle
    • Pratima Nallagatla
    • Tanja A. Gruber
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16