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Showing 1–7 of 7 results

Advanced filters: Author: Mu-En Chen Clear advanced filters

Brachiopod genome unveils the evolution of BMP signalling in bilaterian body patterning

A chromosome-level brachiopod genome reveals deep conservation of BMP-mediated dorsal–ventral patterning and neural inhibition, suggesting the spiralian ancestor retained the ancestral mechanism in bilaterians.

Thomas D. Lewin
Tosuke Sakagami
Yi-Jyun Luo
ResearchOpen Access12 Mar 2026
Nature Communications

P: 1-19
Targeting SREBP-dependent lipogenesis potentiates the anti-tumor activity of docetaxel by increasing membrane permeability and intracellular drug accumulation

Jiaqi Chen
Mu-En Wang
Ming Chen
ResearchOpen Access04 Oct 2025
Oncogene

Volume: 44, P: 4405-4412
Heat shock factor 1 directly regulates transsulfuration pathway to promote prostate cancer proliferation and survival

HSF1 regulates the conversion of homocysteine to cystathionine in the trans-sulfuration pathway by altering levels of cystathionine-β-synthase (CBS), and targeting CBS decreases pancreatic cancer growth while leaving benign prostate cells largely unaffected.

J. Spencer Hauck
David Moon
Jiaoti Huang
ResearchOpen Access03 Jan 2024
Communications Biology

Volume: 7, P: 1-13
Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

Mu-En Wang
Brijesh K. Singh
Chih-Hsien Chiu
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-13
Fatty acids suppress the steroidogenesis of the MA-10 mouse Leydig cell line by downregulating CYP11A1 and inhibiting late-stage autophagy

Chien Huang
Hsiu-Ju Hsu
Chih-Hsien Chiu
ResearchOpen Access15 Jun 2021
Scientific Reports

Volume: 11, P: 1-12
Kisspeptin-Activated Autophagy Independently Suppresses Non-Glucose-Stimulated Insulin Secretion from Pancreatic β-Cells

Chien Huang
Hao-Yi Wang
Chih-Hsien Chiu
ResearchOpen Access25 Nov 2019
Scientific Reports

Volume: 9, P: 1-11
Effect of Alzheimer's Disease Risk Variant rs3824968 at SORL1 on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan

Chu-Chung Huang
Mu-En Liu
Ching-Po Lin
ResearchOpen Access21 Mar 2016
Scientific Reports

Volume: 6, P: 1-8