Polo-like kinase 1 (PLK1) is recruited to kinetochores during mitosis, where it is required for proper chromosome alignment. Leeet al. show that the chromatin-remodelling factor RSF1 is required for PLK1 recruitment, and that this function depends on phosphorylation of RSF1 by the mitotic kinase CDK1.
- Ho-Soo Lee
- Yong-Yea Park
- Hyeseong Cho