Betty Tsao, Jian Zhao, Nan Shen and colleagues show that a common missense variant in NCF1 confers susceptibility to multiple autoimmune diseases. This variant, which leads to reduced production of reactive oxygen species, accounts for the strong association signal previously identified in the GTF2IRD1–GTF2I region at 7q11.23.
- Jian Zhao
- Jianyang Ma
- Betty P Tsao
