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Advanced filters: Author: Nandini Krishnamoorthy Clear advanced filters

Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma

Recurrent infections with respiratory syncytial virus (RSV) early in life increase susceptibility to asthma. Nandini Krishnamoorthy et al. show that RSV infection of young mice impairs maternally transferred tolerance to allergens. Regulatory T (T_reg) cells in infected mice have impaired suppressor function and adopt a T_H2-like phenotype.

Nandini Krishnamoorthy
Anupriya Khare
Prabir Ray
Research09 Sept 2012
Nature Medicine

Volume: 18, P: 1525-1530
Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity

The serial assessment of the functional parameters of leukocytes isolated via an inertial microfluidic system from 50 μl of peripheral blood from sepsis patients provides significantly more prognostic information than leukocyte counting.

Bakr Jundi
Hyunryul Ryu
Bruce D. Levy
Research11 Nov 2019
Nature Biomedical Engineering

Volume: 3, P: 961-973
Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma

Nandini Krishnamoorthy
Timothy B Oriss
Prabir Ray
Research04 May 2008
Nature Medicine

Volume: 14, P: 565-573

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