Mobilization of immature neutrophils (imNeu) can migrate from bone marrow (BM) to circulation and inflamed tissues. However, the mechanism of its mobilization and function remains unknown. Here the authors identify ILC1 mediates IL-10 producing imNeu mobilization to inflamed tissue via IFN-γ, thus tempering the acute inflammation.
- Kenshiro Matsuda
- Natsuki Ide
- Akira Shibuya
