Currently there is no single imaging system that can offer adequate spatial and temporal resolution to accurately assess many of the important factors involved in peripheral arterial diseases. Here, an epifluorescence imaging approach is offered that overcomes many of the current limitations and uses the near-infrared fluorescence of single-walled carbon nanotubes as fluorophores in the second near-infrared window (beyond 1,000 nm). Its use is demonstrated for imaging blood vessels in mouse hindlimb vasculatures millimeters deep in vivo.
- Guosong Hong
- Jerry C Lee
- Hongjie Dai
