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Showing 1–3 of 3 results

Advanced filters: Author: Nico Carlson Clear advanced filters

Impact of pre-adapted HIV transmission

Jonathan Carlson and colleagues report that pre-adaptation of HIV to a recipient's major histocompatibility complex class I alleles impairs immune control of the virus.

Jonathan M Carlson
Victor Y Du
Paul A Goepfert
Research16 May 2016
Nature Medicine

Volume: 22, P: 606-613
Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system

Toxin-antitoxin systems make up a branch of the bacterial anti-phage immune system. Here, Johannesman et al demonstrate that some phages have co-opted an orphan antitoxin to counter a DNA ADP-ribosyltransferase defense system.

Anna Johannesman
Leila C. Awasthi
Michele LeRoux
ResearchOpen Access13 Feb 2025
Nature Communications

Volume: 16, P: 1-11
Molecular characterization of colorectal cancer related peritoneal metastatic disease

Colorectal cancer can lead to the development of peritoneal metastases, which are associated with worse disease outcome. Here, the authors characterize peritoneal metastases from 52 patients using RNA-seq and mutational sequencing and show a distinct molecular subtype.

Kristiaan J. Lenos
Sander Bach
Louis Vermeulen
ResearchOpen Access04 Aug 2022
Nature Communications

Volume: 13, P: 1-14