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Showing 1–8 of 8 results

Advanced filters: Author: Nicolas Massaly Clear advanced filters

Chronic pain could be eased by uncoupling the sensory and emotional experiences

Researchers identify the neurons involved in the emotional distress associated with pain, and design a genetic approach that could soothe suffering without opioid drugs.

Nicolas Massaly
Monique L. Smith
News & Views07 Jan 2026
Nature

Volume: 649, P: 832-833
Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons

The role of dorsal hippocampus in driving reinforcement remains to be determined. Here, authors show that dorsal hippocampus-driven reinforcing behaviors are mediated via inputs to dynorphin neurons in the dorsal medial nucleus accumbens.

Khairunisa Mohamad Ibrahim
Nicolas Massaly
Jose A. Morón
ResearchOpen Access29 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Modulation of dorsal hippocampal SK2 channels regulates morphine-enhanced neuronal oscillations and morphine-induced contextual memory encoding and retrieval

Khairunisa Mohamad Ibrahim
Dominika J. Burek
Jose A. Morón
ResearchOpen Access20 Nov 2025
Scientific Reports

Volume: 15, P: 1-16
Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry

Stopping chronic opioid use can lead to withdrawal. Here, authors show in mice that dampening activity of spinally projecting locus coeruleus neurons, targeting microglia, or blocking pannexin-1 channels alleviates opioid withdrawal.

Charlie H. T. Kwok
Erika K. Harding
Tuan Trang
ResearchOpen Access24 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior

Markovic et al. demonstrate in rodents that anhedonia-like states in inflammatory pain are mediated through increased inhibitory control and subsequent diminished activity of mesolimbic dopamine neurons.

Tamara Markovic
Christian E. Pedersen
Jose A. Morón
Research18 Oct 2021
Nature Neuroscience

Volume: 24, P: 1601-1613
A locus coeruleus to dorsal hippocampus pathway mediates cue-induced reinstatement of opioid self-administration in male and female rats

Tamara Markovic
Jessica Higginbotham
Jose A. Morón
Research19 Feb 2024
Neuropsychopharmacology

Volume: 49, P: 915-923
Involvement of Protein Degradation by the Ubiquitin Proteasome System in Opiate Addictive Behaviors

Nicolas Massaly
Lionel Dahan
Bernard Frances
Research21 Nov 2012
Neuropsychopharmacology

Volume: 38, P: 596-604
Morphine-Associated Contextual Cues Induce Structural Plasticity in Hippocampal CA1 Pyramidal Neurons

Amanda K Fakira
Nicolas Massaly
Jose A Morón
Research10 May 2016
Neuropsychopharmacology

Volume: 41, P: 2668-2678