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Showing 1–3 of 3 results
Advanced filters: Author: Niklas Kupfer Clear advanced filters

  • DNA damage threatens genome stability, but its dynamics in living systems remain difficult to track. Here, the authors engineer MCPH1-based protein probes that specifically recognize γH2AX, enabling real-time visualization and mapping of DNA damage across diverse cellular and organismal contexts.

    • Richard Cardoso da Silva
    • Kristeli Eleftheriou
    • Tuncay Baubec
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Systemic AL amyloidosis is one of the most frequently diagnosed forms of systemic amyloidosis. Here the authors analyse the structures of AL amyloid fibrils with different light chain mutations and show that the mutations contribute to defining the fibril structure in different patients.

    • Sara Karimi-Farsijani
    • Peter Benedikt Pfeiffer
    • Marcus Fändrich
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-8