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Nature Ecology & Evolution (2)
Molecular Psychiatry (1)

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Showing 1–3 of 3 results

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Reply to: Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease

Juan Antonio Rodríguez
Xavier Farré
Arcadi Navarro
Research24 Jun 2019
Nature Ecology & Evolution

Volume: 3, P: 994-995
Antagonistic pleiotropy and mutation accumulation influence human senescence and disease

Evolutionary explanations for ageing suggest late-onset deleterious mutations may be tolerated or even favoured by selection. Here, data from human genome-wide association studies are used to support these evolutionary predictions.

Juan Antonio Rodríguez
Urko M. Marigorta
Arcadi Navarro
Research30 Jan 2017
Nature Ecology & Evolution

Volume: 1, P: 1-5
Monoallelic loss-of-function variants in GSK3B lead to autism and developmental delay

Senwei Tan
Qiumeng Zhang
Hui Guo
Research29 Oct 2024
Molecular Psychiatry

Volume: 30, P: 1952-1965