Nature Search

Dietary carbohydrates alter immune-modulatory functionalities and DNA inversions in Bacteroides thetaiotaomicron

Here, the authors characterize how different dietary components lead to functional alterations in the gut symbiont Bacteroides thetaiotaomicron, showing effects on the orientation of phase variable regions in humans, in vivo, and in vitro, and on modulating the bacterium´s proteome and immune-modulatory functionality.

Noa Gal-Mandelbaum
Shaqed Carasso
Naama Geva-Zatorsky
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-19
A lifespan clock tells the biology of time

A full‑lifecycle clock derived from millions of routine clinical records reveals that human development and aging form a continuous physiological trajectory, enabling early disease detection and mechanistic insights for preventive and precision health.

Noa Rappaport
Annalise Schweickart
Nathan D. Price
News & Views08 Dec 2025
Nature Medicine

Volume: 31, P: 3992-3993
Real-world effectiveness of a single dose of mpox vaccine in males

Effectiveness of one subcutaneous dose of MVA-BN, the smallpox and mpox vaccine, was estimated to be 86% in a cohort of vaccine-eligible males in Israel, supporting its use to curtail the outbreak of mpox virus.

Yael Wolff Sagy
Roy Zucker
Doron Netzer
Research31 Jan 2023
Nature Medicine

Volume: 29, P: 748-752
Three lncRNAs promote PUM protein condensation and germline differentiation

RNA-binding FBF proteins control germline stem cell differentiation. Here, the authors show that three long non-coding RNAs bind, condense, and thus inhibit FBFs to promote the transition of germline stem cells into meiosis.

Roni Falk
Noa Gilad
Yonatan B. Tzur
ResearchOpen Access24 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

Integrated analyses reveal that multiomics captured the heterogeneity of metabolic states accompanying obesity and changes in metabolic health in response to lifestyle intervention that are not apparent in body mass index measurements.

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
ResearchOpen Access20 Mar 2023
Nature Medicine

Volume: 29, P: 996-1008
Author Correction: Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Tomasz Wilmanski
Christian Diener
Nathan D. Price
Amendments and Corrections18 Mar 2021
Nature Metabolism

Volume: 3, P: 586
Blood metabolome predicts gut microbiome α-diversity in humans

Multiomics reveals that almost half of gut microbiome diversity in humans can be explained by 40 blood metabolites.

Tomasz Wilmanski
Noa Rappaport
Nathan D. Price
Research02 Sept 2019
Nature Biotechnology

Volume: 37, P: 1217-1228
Microbial community-scale metabolic modelling predicts personalized short-chain fatty acid production profiles in the human gut

Microbial community-scale metabolic modelling predicts person-specific short-chain fatty acid profiles and can be used to estimate the impact of dietary, prebiotic and probiotic interventions.

Nick Quinn-Bohmann
Tomasz Wilmanski
Sean M. Gibbons
Research24 Jun 2024
Nature Microbiology

Volume: 9, P: 1700-1712
Genome–microbiome interplay provides insight into the determinants of the human blood metabolome

Diener and Dai et al. analyse blood metabolites from 1,569 individuals and identify metabolites associated with the microbiome, host genetics or under hybrid genetic–microbiome control.

Christian Diener
Chengzhen L. Dai
Sean M. Gibbons
Research10 Nov 2022
Nature Metabolism

Volume: 4, P: 1560-1572
Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

A new culture system makes it possible to grow mouse embryos and study their development outside the uterus up to the point of late organogenesis.

Alejandro Aguilera-Castrejon
Bernardo Oldak
Jacob H. Hanna
Research17 Mar 2021
Nature

Volume: 593, P: 119-124
The geometry of clinical labs and wellness states from deeply phenotyped humans

Longitudinal multi-omics measurements are highly valuable in studying heterogeneity in health and disease phenotypes. Here, the authors apply Pareto Task Inference to analyze the clinical lab tests of 3094 individuals and find three wellness states, and one aberrant health state defining this cohort.

Anat Zimmer
Yael Korem
Nathan D. Price
ResearchOpen Access11 Jun 2021
Nature Communications

Volume: 12, P: 1-13
Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Increasing compositional uniqueness of the gut microbiome, and corresponding changes in microbial metabolites in the blood, are identified as a signature of healthy ageing in humans.

Tomasz Wilmanski
Christian Diener
Nathan D. Price
Research18 Feb 2021
Nature Metabolism

Volume: 3, P: 274-286
Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis

Andrew T. Magis
Noa Rappaport
Nathan D. Price
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-6
Microtubules orchestrate local translation to enable cardiac growth

New contractile units are required during cardiac hypertrophy, though it remains unclear precisely where and how these new sarcomeres are added. Here the authors reveal that in the heart, microtubules spatiotemporally regulate mRNAs and ribosomes to build new sarcomeres, a role which is essential for growth.

Emily A. Scarborough
Keita Uchida
Benjamin L. Prosser
ResearchOpen Access11 Mar 2021
Nature Communications

Volume: 12, P: 1-13
Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses

Metabolic syndrome in horses has distinct metabotypes tied to triglycerides or bile acids. Multi-omic profiling revealed links to insulin, genetics, and microbiota, positioning horses as model for metabolic syndrome diagnostics and therapies.

Callum G. Donnelly
Sichong Peng
Carrie J. Finno
ResearchOpen Access27 Nov 2025
Communications Biology

Volume: 8, P: 1-9
Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis

Koren and Feldman et al. report a distinct population of Thy1-expressing stem cells in the basal layer of the mouse epidermis. These stem cells do not compete neutrally and contribute long-term to both epidermal replenishment and wound repair.

Elle Koren
Alona Feldman
Yaron Fuchs
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects

Noa Mandelbaum
Lihan Zhang
Naama Geva-Zatorsky
ResearchOpen Access03 Jun 2023
npj Biofilms and Microbiomes

Volume: 9, P: 1-11
Second breast cancer: recurrence score results, clinicopathologic characteristics, adjuvant treatments, and outcomes—exploratory analysis of the Clalit registry

Shlomit S. Shachar
Michelle Leviov
Salomon M. Stemmer
ResearchOpen Access30 Sept 2023
npj Breast Cancer

Volume: 9, P: 1-7
Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Integrated systems analysis on mouse liver proteomic and transcriptomic data of multiple lifespan-extending interventions highlights the overarching biological processes involved in aging and longevity.

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
ResearchOpen Access22 Jul 2023
Communications Biology

Volume: 6, P: 1-15
Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

Methods for direct conversion of fibroblasts to other cell types using pluripotency-associated factors generate a transient pluripotent state.

Itay Maza
Inbal Caspi
Jacob H Hanna
Research22 Jun 2015
Nature Biotechnology

Volume: 33, P: 769-774
The transition from genomics to phenomics in personalized population health

This Perspective reviews large-scale genomics and longitudinal phenomics efforts and the insights they can provide into wellness. The authors describe their vision for the transformation of the current health care from disease-oriented to data-driven, wellness-oriented and personalized population health.

James T. Yurkovich
Simon J. Evans
Leroy E. Hood
Reviews13 Dec 2023
Nature Reviews Genetics

Volume: 25, P: 286-302
Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
Amendments and CorrectionsOpen Access27 Nov 2023
Communications Biology

Volume: 6, P: 1
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Laura Heath
John C. Earls
Yi Zhao
ResearchOpen Access12 Apr 2022
Scientific Reports

Volume: 12, P: 1-17
Risk factors for severe COVID-19 differ by age for hospitalized adults

Sevda Molani
Patricia V. Hernandez
Jennifer J. Hadlock
ResearchOpen Access28 Apr 2022
Scientific Reports

Volume: 12, P: 1-9
Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance

Talita Jiryis
Noa Magal
Roee Admon
ResearchOpen Access21 Oct 2022
Scientific Reports

Volume: 12, P: 1-10
Newly diagnosed myeloma patients with low-burden disease may benefit from tandem autologous stem cell transplantation: results of long-term follow-up

Noam Benyamini
Noa Lavi
Tamar Katz
Correspondence16 Sept 2019
Bone Marrow Transplantation

Volume: 55, P: 1200-1202
The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death

Ido Livneh
Victoria Cohen-Kaplan
Aaron Ciechanover
ReviewsOpen Access22 Jul 2016
Cell Research

Volume: 26, P: 869-885

Search

Dietary carbohydrates alter immune-modulatory functionalities and DNA inversions in Bacteroides thetaiotaomicron

A lifespan clock tells the biology of time

Real-world effectiveness of a single dose of mpox vaccine in males

Three lncRNAs promote PUM protein condensation and germline differentiation

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

Author Correction: Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Blood metabolome predicts gut microbiome α-diversity in humans

Microbial community-scale metabolic modelling predicts personalized short-chain fatty acid production profiles in the human gut

Genome–microbiome interplay provides insight into the determinants of the human blood metabolome

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

The geometry of clinical labs and wellness states from deeply phenotyped humans

Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis

Microtubules orchestrate local translation to enable cardiac growth

Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses

Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis

Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects

Second breast cancer: recurrence score results, clinicopathologic characteristics, adjuvant treatments, and outcomes—exploratory analysis of the Clalit registry

Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

The transition from genomics to phenomics in personalized population health

Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Risk factors for severe COVID-19 differ by age for hospitalized adults

Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance

Newly diagnosed myeloma patients with low-burden disease may benefit from tandem autologous stem cell transplantation: results of long-term follow-up

The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death

Search

Quick links

Search

Filter By:

Search

Quick links