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Showing 1–3 of 3 results
Advanced filters: Author: Noam Pilpel Clear advanced filters

  • The accumulation of senescent cells within tissues plays a role in numerous age-related pathologies. Yosef and Pilpel et al. demonstrate that the resistance of these cells to apoptosis is driven by upregulation of survival proteins, whose pharmacological inhibition triggers senescent cell elimination in mice.

    • Reut Yosef
    • Noam Pilpel
    • Valery Krizhanovsky
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • Here, the authors estimate mammalian biomass from the 1850’s to today, tracking an increase of over five-fold in human and domesticated mammal biomass and a two-fold decrease in wild mammal biomass. Recent trends of increase in some wild marine mammals are seen to be still far below historic levels. The results of this study are caveated due to limited historic data but have implications for conservation efforts.

    • Lior Greenspoon
    • Noam Ramot
    • Ron Milo
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-7

  • Here, analyzing data from a six-month clinical trial in pre-diabetes, the authors found 166 of 2,803 measured features, including oral and gut microbiome, metabolites and cytokines, significantly changed in response to dietary interventions; highlighting the microbiome’s role in cardiometabolic health and revealing potential therapeutic avenues.

    • Saar Shoer
    • Smadar Shilo
    • Eran Segal
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14