Basal-like breast cancers are associated with a poor disease-free and overall survival. The pathologic features of breast carcinomas classified by immunohistochemical and gene-expression profiling criteria are critically discussed. The authors emphasize that basal-like tumors display a spectrum of morphologic and clinical characteristics, and that the heterogenous nature of these tumors means the most prognostically relevant subsets have yet to be defined.
- Oluwole Fadare
- Fattaneh A Tavassoli
