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Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization

Intracellular Salmonella enterica uses a type III secretion system to secrete more than 30 effector proteins into host cells. Here, Newson et al. generate six mutant strains deficient in different sets of effectors, thus providing insights on the interdependency or functional redundancy between effectors in vivo.

Joshua P. M. Newson
Flavia Gürtler
Wolf-Dietrich Hardt
ResearchOpen Access06 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Structure of Amylopectin

KURT H. MEYER
P. GÜRTLER
P. BERNFELD
Research27 Dec 1947
Nature

Volume: 160, P: 900-901
Multiple ionization of atom clusters by intense soft X-rays from a free-electron laser

H. Wabnitz
L. Bittner
M. Yurkov
Research05 Dec 2002
Nature

Volume: 420, P: 482-485
Charting cellular identity during human in vitro β-cell differentiation

Single-cell transcriptional profiling of in vitro human pancreatic β-cell differentiation reveals progenitor and terminal fates, produces a detailed time course of endocrine induction and underpins a lineage model.

Adrian Veres
Aubrey L. Faust
Douglas A. Melton
Research08 May 2019
Nature

Volume: 569, P: 368-373

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