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Showing 1–7 of 7 results
Advanced filters: Author: Parameswaran Nair Clear advanced filters

  • There are similarities in airway inflammatory endotype between eosinophilic granulomatosis with polyangiitis (EGPA) and type 2 eosinophilic asthma. Here, the authors perform single-cell transcriptomics to compare EGPA with severe eosinophilic asthma and find differences in the innate immune cell populations and use mouse models to characterise the function and phenotype of these cells.

    • Cong Dong
    • Bingtai Lu
    • Qingling Zhang
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-20

  • Myeloid cells modulate the immune response within the tumour microenvironment, but the underlying mechanisms remain largely unknown. Here, the authors show that Fcmr – the putative receptor for soluble IgM – is a potent negative regulator of anti-tumour immunity.

    • Shawn P. Kubli
    • Larsen Vornholz
    • Tak W. Mak
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • Intracellular, intercellular and extracellular silicon interfaces enable light-controlled non-genetic modulation of intracellular calcium dynamics, of cellular excitability, of neurotransmitter release from brain slices, and of brain activity in vivo.

    • Yuanwen Jiang
    • Xiaojian Li
    • Bozhi Tian
    Research
    Nature Biomedical Engineering
    Volume: 2, P: 508-521

  • The rich ethnolinguistic and sociocultural differences that exist in India offers a unique opportunity to study human diversity. With the whole genomes of 10,000 healthy and unrelated Indians from 83 populations, the GenomeIndia project captures the genetic diversity of one of the highly underrepresented populations in the global genomics landscape.

    • Chandrika Bhattacharyya
    • Krithika Subramanian
    • Bratati Kahali
    Comments & Opinion
    Nature Genetics
    Volume: 57, P: 767-773

  • Segmented polyurethane prepared using a novel chain extender, calcium lactate along with polytetramethylene glycol and hexamethylene diisocyanate. The properties of the synthesized polyurethane compared with that of polyurethane without any calcium. The prepared polymer has high glass transition temperature and storage modulus, and has improved mechanical properties. In vitro hemocompatibility evaluation reveals that the material is blood compatible and does not induce any hemolysis to blood.

    • Priya A Nair
    • Parameswaran Ramesh
    Research
    Polymer Journal
    Volume: 44, P: 1009-1014