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Showing 1–3 of 3 results
Advanced filters: Author: Paul Soudier Clear advanced filters

  • The reconstitution of complex biological processes in cell-free systems can support the detailed characterisation of biochemical mechanisms which are difficult to probe in vivo. Here authors present an all-cell-free T7 phage cycle, consisting of cell-sized liposomes encapsulating a cell-free gene expression reaction and a phage receptor at the membrane.

    • Antoine Levrier
    • Paul Soudier
    • Vincent Noireaux
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-12

  • Cell-free lysates are a major platform for in vitro protein production but batch-to-batch variation makes production difficult to predict. Here the authors develop an active learning approach to optimising buffer conditions to bring homemade lysates up to commercial production potential.

    • Olivier Borkowski
    • Mathilde Koch
    • Jean-Loup Faulon
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8

  • So far, synthetic genetic circuits have relied on digital logic for information processing. Here the authors present metabolic perceptrons that use analog weighted adders to vary the contributions of multiple inputs, resulting in different classification functions.

    • Amir Pandi
    • Mathilde Koch
    • Jean-Loup Faulon
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13