Torras-Llort et al. find that the chromatin binding protein Barrier-to-Autointegration Factor (BAF) associates with centromeres and is required for proper centromere assembly and function in Drosophila. They show that disruption of centromeric BAF localization prevents PP2A inactivation in mitosis compromising global BAF phosphorylation and leading to delayed anaphase onset and nuclear envelope defects.
- Mònica Torras-Llort
- Sònia Medina-Giró
- Fernando Azorín
