We evaluated the biocompatibility and biodegradability of implants made of pure PLA and a PLA/PCL blend compatibilized with poly(ɛ-caprolactone-b-tetrahydrofuran) in horses by physical examination, plasma fibrinogen, thermographic, mechanical nociceptive threshold, and ultrasound tests. We also conducted histopathological and surface morphology analyses. Pure PLA and PLA/PCL blends subcutaneously implanted stimulated a minimal inflammatory response and supported cellular infiltration, being biocompatible and biodegradable in horses, with potential for use in equine medicine.
- Júlia R. G. Carvalho
- Gabriel Conde
- Guilherme C. Ferraz
