Nature Search

Genomic platform specific polygenic risk scores impact breast cancer risk stratification

Ho et al. investigate the impact of choice of sequencing platform on identification of specific variants for breast cancer risk stratification. Platform-specific variability is found to influence PRS313 estimates, potentially reclassifying individuals around clinically relevant thresholds.

Peh Joo Ho
Alexis Jiaying Khng
Jingmei Li
ResearchOpen Access12 Dec 2025
Communications Medicine

Volume: 6, P: 1-10
Profile of the BREATHE cohort for risk-based breast screening in Singapore

Peh Joo Ho
Jenny Liu
Mikael Hartman
ResearchOpen Access10 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women

Polygenic risk scores predict the likelihood that an individual will develop a certain cancer, however these are often specific for a given population. Here, the authors show that a risk score developed to assess the risk of breast cancer in European women can also predict risk in Asian populations.

Weang-Kee Ho
Min-Min Tan
Antonis C. Antoniou
ResearchOpen Access31 Jul 2020
Nature Communications

Volume: 11, P: 1-11
Correction: Profile of the BREATHE cohort for risk-based breast screening in Singapore

Peh Joo Ho
Jenny Liu
Mikael Hartman
Amendments and CorrectionsOpen Access20 Nov 2025
Scientific Reports

Volume: 15, P: 1
Author Correction: Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

Naomi Wilcox
Martine Dumont
Jacques Simard
Amendments and CorrectionsOpen Access26 Sept 2023
Nature Genetics

Volume: 55, P: 2009
Determinants of breast size in Asian women

Li Yan Lim
Peh Joo Ho
Jingmei Li
ResearchOpen Access19 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
Incidence of breast cancer attributable to breast density, modifiable and non-modifiable breast cancer risk factors in Singapore

Peh Joo Ho
Hannah Si Hui Lau
Jingmei Li
ResearchOpen Access16 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
Impact of deviation from guideline recommended treatment on breast cancer survival in Asia

Peh Joo Ho
Samuel Guan Wei Ow
Mikael Hartman
ResearchOpen Access28 Jan 2020
Scientific Reports

Volume: 10, P: 1-12
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

Meta-analysis of three large whole-exome sequencing datasets highlights protein-truncating and rare missense variants associated with breast cancer susceptibility.

Naomi Wilcox
Martine Dumont
Jacques Simard
ResearchOpen Access17 Aug 2023
Nature Genetics

Volume: 55, P: 1435-1439
Comparison of self-reported and register-based hospital medical data on comorbidities in women

Peh Joo Ho
Chuen Seng Tan
Jingmei Li
ResearchOpen Access05 Mar 2019
Scientific Reports

Volume: 9, P: 1-9

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