Nature Search

Spermidine mediates acetylhypusination of RIPK1 to suppress diabetes onset and progression

Zhang et al. show that the activation of RIPK1 is suppressed by acetylhypusination in a spermidine-dependent manner. Disruption of this axis contributes to RIPK1-mediated vascular pathology to promote insulin resistance and diabetic kidney pathology.

Tian Zhang
Weixin Fu
Junying Yuan
Research07 Nov 2024
Nature Cell Biology

Volume: 26, P: 2099-2114
Li⁺-migration influencing factors and non-destructive life extension of quasi-solid-state polymer electrolytes

Polymer electrolytes are promising but are limited by narrow electrochemical window. Here, authors develop a family of in situ polymerized gel electrolytes with long term stability up to 5.0 V and develop a non-destructive life extension strategy through freezing the cells.

Peiying Li
Jinjin Hao
Weidong Zhou
ResearchOpen Access19 Apr 2025
Nature Communications

Volume: 16, P: 1-14
Interconnected nanoconfining pore networks enhance catalyst CO₂ interaction in electrified reactive capture

Electrified reactive capture converts CO₂ from carbonate solutions but suffers from low Faradaic efficiency. Here, the authors report a templated synthesis with defined pores and Ni single atoms to accumulate CO₂, achieving 46% energy efficiency to syngas at 300 mA/cm²

Hengzhou Liu
Lun An
Edward H. Sargent
ResearchOpen Access04 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Novel Flexible Ureteroscopic System for intrarenal pelvic and intracaliceal pressure measurement in porcine models

Yaoji Yuan
Peiying Chen
Guibin Xu
ResearchOpen Access12 May 2025
Scientific Reports

Volume: 15, P: 1-12
National identities of China and the U.S. in Kazakhstani media: a post-Russia–Ukraine war analysis

Jie Li
Peiying Lv
Yuan Tao
ResearchOpen Access28 Nov 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-14
Federated learning for predicting clinical outcomes in patients with COVID-19

Federated learning, a method for training artificial intelligence algorithms that protects data privacy, was used to predict future oxygen requirements of symptomatic patients with COVID-19 using data from 20 different institutes across the globe.

Ittai Dayan
Holger R. Roth
Quanzheng Li
Research15 Sept 2021
Nature Medicine

Volume: 27, P: 1735-1743
A stress-induced miR-31–CLOCK–ERK pathway is a key driver and therapeutic target for skin aging

Changes in hair and skin can be the most obvious and earliest signs of aging. The authors report that skin and hair follicle stem cell (HFSC) aging is driven by stress-induced upregulation of miR-31, which targets Clock to activate MAPK/ERK and deplete HFSCs via transepidermal elimination. Blocking the pathway with MAPK/ERK inhibitors protects against skin aging.

Yao Yu
Xia Zhang
Liang Zhang
Research16 Aug 2021
Nature Aging

Volume: 1, P: 795-809
Development and validation of a clinical predictive model for high-volume lymph node metastasis of papillary thyroid carcinoma

Hanlin Zhu
Haifeng Zhang
Zhijiang Han
ResearchOpen Access09 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Horizontally arranged zinc platelet electrodeposits modulated by fluorinated covalent organic framework film for high-rate and durable aqueous zinc ion batteries

Rechargeable aqueous zinc-ion batteries are promising but the zinc anode suffers from dendrite growth and electrolyte corrosion. Here, the authors develop a fluorinated covalent organic framework film as a protective layer for aqueous zinc anode battery.

Zedong Zhao
Rong Wang
Zaiping Guo
ResearchOpen Access16 Nov 2021
Nature Communications

Volume: 12, P: 1-14
Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion

Macromolecular aggregates may have played an important role in the origin of life. Here, the authors report hydrophobic-cationic peptides that form insoluble aggregates, which reversibly accrete RNA on their surfaces, and enhance RNA polymerization by a ribozyme.

Peiying Li
Philipp Holliger
Shunsuke Tagami
ResearchOpen Access03 Jun 2022
Nature Communications

Volume: 13, P: 1-11
Nitrogen cycles in global croplands altered by elevated CO₂

Current understanding of how the cropland nitrogen cycle will respond to elevated atmospheric CO₂ is limited. By modelling global nitrogen budgets under elevated CO₂ and providing a monetized impact assessment, this study shows the synergistic effects of elevated CO₂ alone on global croplands.

Jinglan Cui
Xiuming Zhang
Baojing Gu
Research22 Jun 2023
Nature Sustainability

Volume: 6, P: 1166-1176
Switching suppression and enhancement of fluorescence and six-wave mixing by phase modulation

Zhiguo Wang
Peng Ying
Yanpeng Zhang
ResearchOpen Access04 Dec 2013
Scientific Reports

Volume: 3, P: 1-5
CD24–p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages

Dongling Li
Minling Hu
Yang Liu
ResearchOpen Access06 Feb 2018
Cell Discovery

Volume: 4, P: 1-19
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

The histone acetyl transferase KAT2A (also known as GCN5) can also catalyse histone succinylation, with the α-KGDH complex providing a local source of succinyl-CoA.

Yugang Wang
Yusong R. Guo
Zhimin Lu
Research06 Dec 2017
Nature

Volume: 552, P: 273-277
Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway

Daisuke Miki
Peiying Zhu
Jian-Kang Zhu
ResearchOpen Access22 Mar 2017
Scientific Reports

Volume: 7, P: 1-11
Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects

Fen Liu
Bofeng Zhu
Buling Wu
ResearchOpen Access01 Aug 2024
International Journal of Oral Science

Volume: 16, P: 1-14
D₅ dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1

Quansheng Lu
Yu Yang
Pedro A Jose
Research21 Feb 2013
Hypertension Research

Volume: 36, P: 684-690
Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying

Sijie Wu
Yao Yu
Liang Zhang
ResearchOpen Access24 May 2022
Cell Discovery

Volume: 8, P: 1-20
GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation

Shupei Wei
Qin Zhao
Nanshan Zhong
ResearchOpen Access09 Aug 2022
Cell Discovery

Volume: 8, P: 1-16
Effects of pyrolysis temperature, feedstock type and compaction on water retention of biochar amended soil

He Huang
Narala Gangadhara Reddy
Ankit Garg
ResearchOpen Access01 Apr 2021
Scientific Reports

Volume: 11, P: 1-19
Effect of exenatide after short-time intensive insulin therapy on glycaemic remission maintenance in type 2 diabetes patients: a randomized controlled trial

Xiulin Shi
Yalin Shi
Xuejun Li
ResearchOpen Access24 May 2017
Scientific Reports

Volume: 7, P: 1-8
Identification of bladder cancer subtypes and predictive model for prognosis, immune features, and immunotherapy based on neutrophil extracellular trap-related genes

Changhong Guo
Peiying Li
Liang Cui
ResearchOpen Access27 Nov 2023
Scientific Reports

Volume: 13, P: 1-18
Deep-learning-enabled brain hemodynamic mapping using resting-state fMRI

Xirui Hou
Pengfei Guo
Hanzhang Lu
ResearchOpen Access21 Jun 2023
npj Digital Medicine

Volume: 6, P: 1-13
Indispensable role of β-arrestin2 in the protection of remifentanil preconditioning against hepatic ischemic reperfusion injury

Yuting Yang
Caiyang Chen
Liqun Yang
ResearchOpen Access14 Feb 2019
Scientific Reports

Volume: 9, P: 1-9
Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke

Michael J. Van Kanegan
Denise E. Dunn
Donald C. Lo
ResearchOpen Access12 May 2016
Scientific Reports

Volume: 6, P: 1-11
Molecular-based approaches to characterize coastal microbial community and their potential relation to the trophic state of Red Sea

Mohd Ikram Ansari
Moustapha Harb
Pei-Ying Hong
ResearchOpen Access11 Mar 2015
Scientific Reports

Volume: 5, P: 1-10
A map of bat virus receptors derived from single-cell multiomics

Tianhang Lv
Xiaoshan Wang
Longqi Liu
ResearchOpen Access14 Jun 2022
Scientific Data

Volume: 9, P: 1-10

Search

Spermidine mediates acetylhypusination of RIPK1 to suppress diabetes onset and progression

Li⁺-migration influencing factors and non-destructive life extension of quasi-solid-state polymer electrolytes

Interconnected nanoconfining pore networks enhance catalyst CO₂ interaction in electrified reactive capture

Novel Flexible Ureteroscopic System for intrarenal pelvic and intracaliceal pressure measurement in porcine models

National identities of China and the U.S. in Kazakhstani media: a post-Russia–Ukraine war analysis

Federated learning for predicting clinical outcomes in patients with COVID-19

A stress-induced miR-31–CLOCK–ERK pathway is a key driver and therapeutic target for skin aging

Development and validation of a clinical predictive model for high-volume lymph node metastasis of papillary thyroid carcinoma

Horizontally arranged zinc platelet electrodeposits modulated by fluorinated covalent organic framework film for high-rate and durable aqueous zinc ion batteries

Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion

Nitrogen cycles in global croplands altered by elevated CO₂

Switching suppression and enhancement of fluorescence and six-wave mixing by phase modulation

CD24–p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway

Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects

D₅ dopamine receptor decreases NADPH oxidase, reactive oxygen species and blood pressure via heme oxygenase-1

Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying

GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation

Effects of pyrolysis temperature, feedstock type and compaction on water retention of biochar amended soil

Effect of exenatide after short-time intensive insulin therapy on glycaemic remission maintenance in type 2 diabetes patients: a randomized controlled trial

Identification of bladder cancer subtypes and predictive model for prognosis, immune features, and immunotherapy based on neutrophil extracellular trap-related genes

Deep-learning-enabled brain hemodynamic mapping using resting-state fMRI

Indispensable role of β-arrestin2 in the protection of remifentanil preconditioning against hepatic ischemic reperfusion injury

Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke

Molecular-based approaches to characterize coastal microbial community and their potential relation to the trophic state of Red Sea

A map of bat virus receptors derived from single-cell multiomics

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