Nature Search

Charting brain morphology in international healthy and neurological populations

Liu et al. report Chinese normative lifespan brain charts showing later neurodevelopmental milestones than those detected in Western cohorts. Individual deviations from these norms are valuable in assessing clinical risk and outcomes.

Zhizheng Zhuo
Li Chai
Yaou Liu
Research29 Dec 2025
Nature Neuroscience

P: 1-15
Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial

Evidence for the treatment of patients with mild-to-moderate COPD is limited. Here, the authors show that long-term treatment with high-dose N-acetylcysteine neither significantly reduced the annual rate of total exacerbations nor improve lung function in patients with mild-tomoderate COPD.

Yumin Zhou
Fan Wu
Li Chen
ResearchOpen Access30 Sept 2024
Nature Communications

Volume: 15, P: 1-11
Exploring the spatial and temporal distribution mechanism and multidimensional influencing factors of traditional villages in the Huaihe River Basin of China based on geographic grids

Yanlong Guo
Peiyu He
Jie Huang
ResearchOpen Access26 Aug 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-19
Unequal air-quality improvement in China

China’s progress in the improvement of air quality masks a widening gap: its heavily polluted, industrial border cities bear a disproportionate health and economic burden, which demands urgent policy shifts to avoid deepening environmental injustice.

Xianmang Xu
Peiyu Zhao
Jin Wang
Comments & Opinion10 Nov 2025
Nature Cities

Volume: 2, P: 1117-1118
Suppression of hypothalamic oestrogenic signal sustains hyperprolactinemia and metabolic adaptation in lactating mice

ERα^vlVMH neurons mediate the inhibitory role of 17β-oestradiol on prolactin production, and this inhibition is lifted in lactating mice to promote lactation-associated metabolic adaptations.

Meng Yu
Bing Feng
Chunmei Wang
Research10 Apr 2025
Nature Metabolism

Volume: 7, P: 759-777
Atomic-scale strain engineering of atomically resolved Pt clusters transcending natural enzymes

Strain engineering is promising for improving catalytic capability of biocatalysts, but it is challenging to modify the atomic-scale strain for specific enzyme-like reactions. Here, the authors report the biocatalysts with atomically-resolved Pt clusters laminated on PdAu nanocrystals and show that the tensile strains contribute to the enzyme-like activities greater than that of natural enzymes.

Ke Chen
Guo Li
Xiao-Dong Zhang
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-18
Interplay between superconductivity and the strange-metal state in FeSe

Superconductivity can emerge from a strange-metal state, but the exact relationship between them is unknown. Now, quantitative measurements reveal the dependence of resistivity in the strange metal on the superconducting transition temperature.

Xingyu Jiang
Mingyang Qin
Zhongxian Zhao
Research16 Jan 2023
Nature Physics

Volume: 19, P: 365-371
Selective regulation of macrophage lipid metabolism via nanomaterials’ surface chemistry

There is a need to understand how nanomaterials interact with biological systems. Here, the authors report the surface chemistry of graphene oxide nanosheets (GOs) influences the structure of low-density lipoprotein and changes lipid metabolism pathways including LDL recognition, uptake, hydrolysis, efflux, and lipid droplet formation.

Junguang Wu
Xuan Bai
Liming Wang
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-18
Synergetic regulation of SEI mechanics and crystallographic orientation for stable lithium metal pouch cells

The application of Li-metal batteries (LMBs) is impeded by unstable solid electrolyte interphase (SEI) and uncontrollable Li dendrites growth. Here, the authors present an YF₃/PMMA composite layer to achieve high-performance LMBs via the synergetic regulation of SEI mechanics and Li crystallography.

Yanhua Zhang
Rui Qiao
Jiangxuan Song
ResearchOpen Access25 May 2024
Nature Communications

Volume: 15, P: 1-12
Electrochemically coupled CH₄ and CO₂ consumption driven by microbial processes

The microbial valorisation of greenhouse gases could offer promising approaches climate change mitigation. Here, authors demonstrate the coupling of methane oxidation and carbon dioxide reduction by microbial consortia, facilitated by the redox cycling of iron minerals.

Yue Zheng
Huan Wang
Feng Zhao
ResearchOpen Access10 Apr 2024
Nature Communications

Volume: 15, P: 1-11
Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

The basis for the diverse peptide-binding modes and the G protein selectivity of peptide GPCRs remains elusive. Here, the authors offer a structural basis for allosteric-like agonism and G protein selectivity of a neuropeptide GPCR, galanin receptor.

Jia Duan
Dan-Dan Shen
Yi Jiang
ResearchOpen Access15 Mar 2022
Nature Communications

Volume: 13, P: 1-13
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

Multi-targeting agonists at GIPR, GLP-1R or GCGR are pursued vigorously. Here, the authors report cryo-EM structures of tirzepatide-bound GIPR and GLP-1R, peptide 20-bound GIPR, GLP-1R and GCGR, revealing the molecular basis of their multiplexed pharmacological actions.

Fenghui Zhao
Qingtong Zhou
Ming-Wei Wang
ResearchOpen Access25 Feb 2022
Nature Communications

Volume: 13, P: 1-16
SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope

Amino acid changes in a newly identified spike epitope enabled the Delta variant to evade a population antibody response.

Ping He
Banghui Liu
Xiaoli Xiong
ResearchOpen Access23 Sept 2022
Nature Microbiology

Volume: 7, P: 1635-1649
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor

The glucagon-like peptide-1 (GLP-1) receptor is a key regulator of glucose homeostasis and a drug target for type 2 diabetes but available GLP-1R agonists are suboptimal due to several side-effects. Here authors report the cryo-EM structure of GLP-1R bound to an ago-allosteric modulator in complex with heterotrimeric G_s which offers insights into the molecular details of ago-allosterism.

Zhaotong Cong
Li-Nan Chen
Ming-Wei Wang
ResearchOpen Access18 Jun 2021
Nature Communications

Volume: 12, P: 1-11
The regulatory and synergistic effects of FBP2 and HKDC1 on glucose metabolism and malignant progression in gastric cancer

Zhiyuan Yu
Rui Li
Peiyu Li
ResearchOpen Access16 Oct 2025
Cell Death & Disease

Volume: 16, P: 1-16
Prediction of response to neoadjuvant chemo-immunotherapy in patients with esophageal squamous cell carcinoma by a rapid breath test

Qi Huang
Zheng Liu
Xiangnan Li
Research04 Jan 2024
British Journal of Cancer

Volume: 130, P: 694-700
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques

A vaccine protecting from SARS-CoV-2 infection is needed. Here the authors generate a replication-incompetent adenovirus based vaccine expressing SARS-CoV-2 spike, show protection from infection in non-human primates, and analyze the immune response after intramuscular and intranasal vaccination.

Liqiang Feng
Qian Wang
Ling Chen
ResearchOpen Access21 Aug 2020
Nature Communications

Volume: 11, P: 1-11
Recognition of methamphetamine and other amines by trace amine receptor TAAR1

We report on the structures of the TAAR1–G-protein complex when bound to methamphetamine and other amines.

Heng Liu
You Zheng
Fei Xu
Research07 Nov 2023
Nature

Volume: 624, P: 663-671
Lanthanide complexes with d-f transition: new emitters for single-emitting-layer white organic light-emitting diodes

Luminescent lanthanide cerium(III) and europium(II) complexes with d-f transition characteristic were demonstrated as new emitters for efficient and color-stable single-emitting-layer white organic light-emitting diodes.

Peiyu Fang
Peihao Huo
Zhiwei Liu
ResearchOpen Access07 Jul 2023
Light: Science & Applications

Volume: 12, P: 1-10
Analysis of postoperative complications and long term survival following radical gastrectomy for patients with gastric cancer

Zhiyuan Yu
Chen Liang
Sixin Zhou
ResearchOpen Access12 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Initial COVID-19 severity influenced by SARS-CoV-2-specific T cells imprints T-cell memory and inversely affects reinfection

Gang Yang
Jinpeng Cao
Zhongfang Wang
ResearchOpen Access29 May 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-13
The effect of prosocial behavior and its intensity on doctors’ performance in an online health community

Peiyu Zhou
Yuguang Xie
Shuping Zhao
ResearchOpen Access04 Jul 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
SARS-CoV-2 vaccination-infection pattern imprints and diversifies T cell differentiation and neutralizing response against Omicron subvariants

Junxiang Wang
Kaiyi Li
Zhongfang Wang
ResearchOpen Access21 Dec 2022
Cell Discovery

Volume: 8, P: 1-13
Low-dose radiation exaggerates HFD-induced metabolic dysfunction by gut microbiota through PA-PYCR1 axis

Characterisation of gut microbiota shows that low-dose radiation enhances the metabolic defects induced by high-fat diet in mice, in a manner involving increased levels of pyrrolidinecarboxylic acid.

Zhao Ju
Peiyu Guo
Ruixue Huang
ResearchOpen Access10 Sept 2022
Communications Biology

Volume: 5, P: 1-17
Low-level light treatment ameliorates immune thrombocytopenia

Jingke Yang
Qi Zhang
Mei X. Wu
ResearchOpen Access30 Nov 2016
Scientific Reports

Volume: 6, P: 1-10
MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis

Wanfu Xu
Zijing Zhang
Sitang Gong
ResearchOpen Access04 May 2017
Cell Death & Disease

Volume: 8, P: e2761

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