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Showing 1–6 of 6 results
Advanced filters: Author: Peter Faries Clear advanced filters

  • Single-cell proteomic and transcriptional profiling of atherosclerotic lesions from human carotid arteries reveals specific features of lesional T cells and macrophages associated with symptomatic disease.

    • Dawn M. Fernandez
    • Adeeb H. Rahman
    • Chiara Giannarelli
    Research
    Nature Medicine
    Volume: 25, P: 1576-1588

  • Barcia Durán, Dayasagar, et al. map the expression of immune checkpoints in human atherosclerosis and examine the influence of lipid-lowering treatments and type 2 diabetes to understand how immune checkpoint inhibitors worsen cardiovascular risk in survivors of cancer.

    • José Gabriel Barcia Durán
    • Dayasagar Das
    • Chiara Giannarelli
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 3, P: 1482-1502

  • Eberhardt et al. show that SARS-CoV-2 infects human coronary lesions where it preferentially targets plaque macrophages, triggering plaque inflammation and potentially leading to acute cardiovascular complications and long-term cardiovascular risks in patients with COVID-19.

    • Natalia Eberhardt
    • Maria Gabriela Noval
    • Chiara Giannarelli
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 2, P: 899-916

  • Amadori et al. show that plasma from patients with atherosclerosis triggers unique inflammatory transcriptomic and signaling signatures in peripheral blood mononuclear cells, which were used for selecting drugs that may be repurposed for the treatment of atherosclerosis.

    • Letizia Amadori
    • Claudia Calcagno
    • Chiara Giannarelli
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 2, P: 550-571

  • Abdominal aortic aneurysm (AAA) is a common condition that can result in aortic rupture and death. AAA-related mortality continues to rise, highlighting the growing need for effective management strategies. In this Review, the authors discuss the current and future diagnostic and therapeutic strategies for the management of AAA, including the potential of new imaging techniques and novel pharmacological agents.

    • Ahmed Klink
    • Fabien Hyafil
    • Zahi A. Fayad
    Reviews
    Nature Reviews Cardiology
    Volume: 8, P: 338-347