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Showing 1–15 of 15 results

Advanced filters: Author: Peter Seubert Clear advanced filters

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Martin Citron
David Westaway
Dennis J. Selkoe
Research01 Jan 1997
Nature Medicine

Volume: 3, P: 67-72
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron
Tilman Oltersdorf
Dennis J. Selkoe
Research17 Dec 1992
Nature

Volume: 360, P: 672-674
The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

Christian Haass
Cynthia A. Lemere
Dennis J. Selkoe
Research01 Dec 1995
Nature Medicine

Volume: 1, P: 1291-1296
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

Peter Seubert
Carmen Vigo-Pelfrey
Dale Schenk
Research24 Sept 1992
Nature

Volume: 359, P: 325-327
Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

Peter Seubert
Tilman Oltersdorf
Dale B. Schenk
Research01 Jan 1993
Nature

Volume: 361, P: 260-263
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games
David Adams
Jun Zhao
Research09 Feb 1995
Nature

Volume: 373, P: 523-527
Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard
Catherine Cannon
Ted Yednock
Research01 Aug 2000
Nature Medicine

Volume: 6, P: 916-919
Seeing the forest but only half the trees?

John C. Marshall
Peter W. Halligan
Research09 Feb 1995
Nature

Volume: 373, P: 521-523
Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

Peter T. Lansbury Jr.
Philip R. Costa
Robert G. Griffin
Research01 Nov 1995
Nature Structural Biology

Volume: 2, P: 990-998
Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Bruce T. Lamb
Sangram S. Sisodia
John D. Gearhart
Research01 Sept 1993
Nature Genetics

Volume: 5, P: 22-30
Purification and cloning of amyloid precursor protein β-secretase from human brain

Sukanto Sinha
John P. Anderson
Varghese John
Research02 Dec 1999
Nature

Volume: 402, P: 537-540
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk
Robin Barbour
Peter Seubert
Research08 Jul 1999
Nature

Volume: 400, P: 173-177
AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

Manon Domise
Sébastien Didier
Valérie Vingtdeux
ResearchOpen Access27 May 2016
Scientific Reports

Volume: 6, P: 1-12
Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy

Brian J. Bacskai
Stephen T. Kajdasz
Bradley T. Hyman
Advertorial01 Mar 2001
Nature Medicine

Volume: 7, P: 369-372
Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Archived vials of cadaveric human growth hormone contain substantial levels of amyloid-β (Aβ) peptides and can seed Aβ plaques in susceptible mice, suggesting that this material could have transmitted Aβ pathology to humans.

Silvia A. Purro
Mark A. Farrow
John Collinge
Research13 Dec 2018
Nature

Volume: 564, P: 415-419

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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Seeing the forest but only half the trees?

Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Purification and cloning of amyloid precursor protein β-secretase from human brain

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

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