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Showing 1–3 of 3 results
Advanced filters: Author: Philip Molden Clear advanced filters

  • RNA compartmentalization is essential for cellular functions and may have played a pivotal role in the emergence of life. However, the consequences of compartmentalization on RNA catalysis have been largely unexplored. Here, partitioning of catalytic RNA in a two-phase aqueous polymer solution increased local RNA concentration, enhancing ribozyme kinetics.

    • Christopher A. Strulson
    • Rosalynn C. Molden
    • Philip C. Bevilacqua
    Research
    Nature Chemistry
    Volume: 4, P: 941-946

  • Group 2 innate lymphoid cells (ILC2s) are generally considered to have pro-tumor functions. However, Belz and colleagues demonstrate that ILC2s have anti-melanoma effects due to their high production of the inflammatory cytokine granulocyte-macrophage colony-stimulating factor in the tumor microenvironment.

    • Nicolas Jacquelot
    • Cyril Seillet
    • Gabrielle T. Belz
    Research
    Nature Immunology
    Volume: 22, P: 851-864