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Showing 1–8 of 8 results
Advanced filters: Author: Pierre Delanaye Clear advanced filters

  • In a new study, Schwartz and colleagues have investigated the best way to estimate glomerular filtration rate (GFR) in children. Having already improved GFR estimation with the use of creatinine-based equations, the investigators now propose a more precise method for cystatin C measurement. The precision of a GFR equation will strongly depend on the analytical precision of the biological variables included.

    • Pierre Delanaye
    • Natalie Ebert
    News & Views
    Nature Reviews Nephrology
    Volume: 8, P: 503-504

  • Various equations have been developed for estimating glomerular filtration rate (GFR), but the issues surrounding GFR estimation are heavily debated. Although many guidelines now recommend the newer MDRD and CKD-EPI equations over the Cockcroft–Gault equation, these equations do fail to provide accurate estimates of GFR in some situations. This article discusses the development of the different equations and describes clinical situations in which the applicability of the equations is questioned.

    • Pierre Delanaye
    • Christophe Mariat
    Reviews
    Nature Reviews Nephrology
    Volume: 9, P: 513-522

  • Transdermal detection of fluorescent markers has potential to provide point-of-care measurement of glomerular filtration rate. However, validation of proposed approaches and confirmation of their clinical utility should be required ahead of their adoption in the clinic.

    • Pierre Delanaye
    • Richard J. Glassock
    News & Views
    Nature Reviews Nephrology
    Volume: 21, P: 285-286

  • Optimal referral of patients who are at risk of kidney failure to nephrologists could improve their long-term outcomes. Various strategies, including the inclusion of kidney failure risk equations in electronic medical records and the active dissemination of clinical practice guidelines, could help to reduce the gap between optimal referral and what currently happens in clinical practice.

    • Nestor Oliva-Damaso
    • Navdeep Tangri
    • Richard J. Glassock
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 19, P: 275-276

  • Estimates of the prevalence of chronic kidney disease (CKD) vary widely, both within and between countries. Here, the authors discuss the origins of this variation, particularly issues relating to the use of estimated glomerular filtration rate, and present solutions for tackling the factors responsible.

    • Richard J. Glassock
    • David G. Warnock
    • Pierre Delanaye
    Reviews
    Nature Reviews Nephrology
    Volume: 13, P: 104-114

  • This Review examines the concept of kidney lifespan and how increases in haemodynamic and metabolic demands in the kidney can lead to nephron overload, which is a common feature of progressive kidney disease and therefore represents a therapeutic target.

    • Valerie A. Luyckx
    • Andrew D. Rule
    • Hans-Joachim Anders
    Reviews
    Nature Reviews Nephrology
    Volume: 18, P: 171-183