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Showing 1–10 of 10 results

Advanced filters: Author: Priyanka Baloni Clear advanced filters

Genome–microbiome interplay provides insight into the determinants of the human blood metabolome

Diener and Dai et al. analyse blood metabolites from 1,569 individuals and identify metabolites associated with the microbiome, host genetics or under hybrid genetic–microbiome control.

Christian Diener
Chengzhen L. Dai
Sean M. Gibbons
Research10 Nov 2022
Nature Metabolism

Volume: 4, P: 1560-1572
The geometry of clinical labs and wellness states from deeply phenotyped humans

Longitudinal multi-omics measurements are highly valuable in studying heterogeneity in health and disease phenotypes. Here, the authors apply Pareto Task Inference to analyze the clinical lab tests of 3094 individuals and find three wellness states, and one aberrant health state defining this cohort.

Anat Zimmer
Yael Korem
Nathan D. Price
ResearchOpen Access11 Jun 2021
Nature Communications

Volume: 12, P: 1-13
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease

Complementary multi-omics approach, in silico metabolic flux, and neuroimaging analyses link the sphingolipid pathway to Alzheimer’s disease pathogenesis with therapeutic targets validated using behavioral assessments in amyloidogenic APP/PS1 mice.

Priyanka Baloni
Matthias Arnold
Rima Kaddurah-Daouk
ResearchOpen Access08 Oct 2022
Communications Biology

Volume: 5, P: 1-13
Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19

The immune cells of individuals with COVID-19 show metabolic changes.

Jihoon W. Lee
Yapeng Su
James R. Heath
Research06 Sept 2021
Nature Biotechnology

Volume: 40, P: 110-120
Meta-analysis of host response networks identifies a common core in tuberculosis

Awanti Sambarey
Abhinandan Devaprasad
Nagasuma Chandra
ResearchOpen Access10 Feb 2017
npj Systems Biology and Applications

Volume: 3, P: 1-12
Rotenone induced acute miRNA alterations in extracellular vesicles produce mitochondrial dysfunction and cell death

Fatema Currim
Josephine Brown-Leung
Jason R. Cannon
ResearchOpen Access27 Mar 2025
npj Parkinson's Disease

Volume: 11, P: 1-17
Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Integrated systems analysis on mouse liver proteomic and transcriptomic data of multiple lifespan-extending interventions highlights the overarching biological processes involved in aging and longevity.

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
ResearchOpen Access22 Jul 2023
Communications Biology

Volume: 6, P: 1-15
Genome-scale metabolic model of the rat liver predicts effects of diet restriction

Priyanka Baloni
Vineet Sangar
Nathan D. Price
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-12
Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
Amendments and CorrectionsOpen Access27 Nov 2023
Communications Biology

Volume: 6, P: 1
Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer’s disease

Nuanyi Liang
Kwangsik Nho
Frank Sacks
ResearchOpen Access29 Jul 2024
Scientific Reports

Volume: 14, P: 1-14